Current areas of special interest include:
- Studies of virulence gene regulation in bacterial pathogens such as Listeria monocytogenes, Corynebacterium dyphteriae and Enterococcus faecalis,
- Research on secreted bacterial virulence factors of Chlamydia spp.,
- Biofilm research including host-pathogen studies of Staphylococcus aureus, Acinetobacter baumannii, Klebsiella pneumoniae, Clostridium difficile, and Mycobacterium tuberculosis biofilms for vaccine development and improved diagnostics, and
- Research on lipopolysaccharide structure and modification in Pseudomonas aeruginosa and others potential agents of biowarfare and emerging diseases.
Other developing interests are:
- Early childhood caries, opportunistic infections affecting immuno-deficient patients
- cancrum oris (noma)
- Endodontic/systemic infections
Approaches include genomic and post-genomic collaborative projects with scientists of the Institute for Genome Science, molecular and cell biology studies, biomathematical and animal modeling approaches and the state-of-the-art imaging methodologies.
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