Ro- Musculoskeletal Pain Lab Publications

Glutamate Receptor/TRP channels

  1. MK Chung, JS Lee, G Duraes, JY Ro (2011) Lipopolysaccharide-induced Pulpitis Up-regulates TRPV1 in Trigeminal Ganglia. Journal of Dental Research, 90:1103-7.
  2. YH Chun and JY Ro (2010) Electrophysiological characterization of the rat trigeminal caudalis (Vc) neurons following intramuscular injection of capsaicin. Neuroscience Lett, 469: 289-93.
  3. JY Ro, JS Lee, and Y Zhang (2009) Activation of TRPV1 and TRPA1 leads to muscle nociception and mechanical hyperalgesia. Pain 144: 270-7.
  4. YH Chun, D Frank, JS Lee, Y Zhang, Q Auh, JY Ro (2008) Peripheral AMPA receptors contribute to muscle nociception and c-fos activation. Neurosci Res 62: 97-104.
  5. JS Lee and JY Ro (2007) Differential regulation of excitatory amino acid receptor subunits following masseter inflammation in trigeminal ganglia. Neurosci Lett. 421:91-95.
  6. JS Lee and JY Ro (2007) Peripheral metabotropic glutamate receptor 5 mediates mechanical hypersensitivity of craniofacial muscle tissue via the PKC dependent mechanisms. Neuroscience 146(1):375-83.
  7. JY Ro, NF Capra, JS Lee, R Masri, and YH Chun, YH (2007) Mechanisms involved in the hypertonic saline-induced muscle nociception and c-Fos like immunoreactivity in rat brainstem neurons. European Journal of Pain 11: 398-405
  8. JY Ro and NF Capra (2006) Assessing mechanical sensitivity of masseter muscle in lightly anesthetized rats: A model for craniofacial muscle hyperalgesia. Neurosci Res 56: 119-123.
  9. JY Ro, M Nies, and Y Zhang (2005) The role of peripehral NMDA receptors in muscle hyperalgesia. NeuroReport 16:485-489.
  10. JY Ro (2005) Bite Force Measurement in Awake Rats: A Behavioral Model for Persistent Orofacial Muscle Pain and Hyperalgesia. J. Orofacial Pain 19:159-167.
  11. NF Capra and JY Ro (2004) Human and animal experimental models of acute and chronic muscle pain: intramuscular algesic injection. Pain 110: 3-7.
  12. M Nies, and JY Ro (2004) Bite force measurements in awake rats. Brain Res. Protocols 12: 180-185.
  13. JY Ro, NF Capra, and R Masri (2004) Contribution of peripheral N-methyl-D-aspartate receptors to c-fos expression in the trigeminal spinal nucleus following acute masseteric inflammation. Neuroscience 123: 213-219.
  14. JY Ro (2003) Contribution of central and peripheral NMDA receptors in craniofacial muscle nociception and edema formation Brain Res. 979: 78-84.
  15. JY Ro, A Harriott, U Crouse, and NF Capra (2003) Innocuous jaw movements increase c-fos expression in trigeminal sensory nuclei produced by masseter muscle inflammation. Pain 104:539-548.
  16. JY Ro, NF Capra, and R Masri (2003) Development of a behavioral assessment of craniofacial muscle pain in lightly anesthetized rats. Pain 104: 179-185

Sex Differences in Pain and Analgesia

  1. JL Saloman, K Niu, and JY Ro (2011) Activation of peripheral delta-opioid receptors leads to anti-hyperalgesic responses in the masseter muscle of male and female rats. Neuroscience, 190:379-85
  2. K Niu, J Saloman, Y Zhang and JY Ro (2011) Sex differences in the contribution of ATP-sensitive K(+) channels in trigeminal ganglia under an acute muscle pain condition. Neuroscience, 180: 344-352.
  3. K Niu and JY Ro (2011) Cytokine levels during masseter inflammation in male and female rats. Neurosci Lett, 487: 223-227.
  4. S Nunez, JS Lee, Y Zhang Y, G Bai and JY Ro (2007) Role of peripheral μ-opioid receptors in inflammatory orofacial muscle pain. Neuroscience 146(3):1346-54.

Nitric Oxide and Pain

  1. YH Chun, JS Lee, Q Auh and JY Ro (2011) Masseter inflammation differentially regulates three nitric oxide synthases in the subnucleus caudalis (Vc) of the trigeminal sensory nuclear complex. Archives of Oral Biology,
  2. JS Lee, Y Zhang, and JY Ro (2008) Involvement of neuronal, inducible, and endothelia nitric oxide synthases in capsaicin-induced muscle hypersensitivity. European Journal of Pain, 13: 924-8.
  3. JY Ro, JS Lee, NF Capra and Y Zhang (2007) Role of soluble guanylate cyclase in the trigeminal subnucleus caudalis in capsaicin-induced muscle hypersensitivity Brain Research, 1184: 141-148

Trigeminal and Cortical Sensory Processing

  1. EP Gardner, JY Ro, KS Babu, S Ghosh (2007) Neurophysiology of prehension. II. Response diversity in primary somatosensory (S-I) and motor (M-I) cortices. Journal of Neurophysiol. 97(2):1656-70.
  2. EP Gardner, KS Babu, SD Reitzen, S Ghosh, AM Brown, J Chen, AL Hall, M Herzlinger, JB Kohlenstein, and JY Ro (2007) Neurophysiology of prehension: I. Posterior parietal cortex and object-oriented hand behaviors. Journal of Neurophysiol. 97(1):387-406.
  3. R Masri, NF Capra, JY Ro and D Dessem (2006) Classification of muscle spindle afferents innervating the masseter muscle in rats. Archives of Oral Biology 51: 740-747.
  4. R Masri, JY Ro, and NF Capra (2005) The effects of experimental muscle pain on amplitude and velocity sensitivity of jaw closing muscle spindle afferents. Brain Res 1050: 138-47.
  5. JY Ro, Y Zhang, and M Nies (2005) Substance P does not play a critical role in neurogenic inflammation in the rat masseter muscle. Brain Res 1047: 38-44
  6. JY Ro, P Svensson, and NF Capra (2002). Effects of experimental muscle pain on electromyographic activity of masticatory muscles in anesthetized rats. Muscle & Nerve 25: 576-584.
  7. EP Gardner, DY Debowy, JY Ro, S Ghosh, KS Babu (2002) Sensory monitoring of prehension in the parietal lobe: a study using digital video. Behav. Brain Res. 135:213-224.
  8. JY Ro and NF Capra (2001) Modulation of jaw muscle spindle activity following intramuscular injections with hypertonic saline. Pain 92:117-127.
  9. DY Debowy, JY Ro, S Gosh, and EP Gardner (2001) Comparison of neuronal firing rates in somatosensory and posterior parietal cortex during prehension. Exp. Brain Res. 137:269-291.
  10. JY Ro, DY Debowy, S Ghosh, and EP Gardner (2000) Depression of neuronal firing rates in somatosensory and posterior parietal cortex during prehension. Exp. Brain Res. 135:1-11
  11. NF Capra, and JY Ro (2000) Experimental muscle pain produces central modulation of proprioceptive signals arising from jaw muscle spindles. Pain 86: 151-162.
  12. JY Ro and NF Capra (1999) Physiological evidence for caudal projections on jaw muscle spindle afferents. Exp. Brain Res. 128: 425-434.
  13. JY Ro and NF Capra (1999) Evidence for subnucleus interpolaris in craniofacial muscle pain mechanisms demonstrated by intramuscular injections with saline. Brain Res. 842:166-183.
  14. EP Gardner, JY Ro, DY Debowy, and S Ghosh (1999) Facilitation of neuronal activity in sensorimotor cortex during prehension. Exp. Brain Res. 127:329-354.
  15. JY Ro, DY Debowy, S Lu, S Ghosh, and EP Gardner (1998). Digital video: A tool for correlating neuronal firing patterns with hand motor behavior. J Neurosci Meth 82: 215-231.
  16. JY Ro and NF Capra (1995). Encoding of jaw movements by central trigeminal neurons with cutaneous receptive fields. Exp. Brain Res. 104: 363-375.
  17. JY Ro and NF Capra (1994). Receptive field properties of trigeminothalamic neurons in the rostral trigeminal sensory nuclei of cats. Somatosen. and Mot. Res. 12: 119-130.
  18. NF Capra, JY Ro, and TD Wax (1994). Physiological identification of movement-related neurons in the spinal trigeminal nucleus of cats. Somatosen. and Mot. Res. 11: 77-88.