Biomaterials & Tissue Engineering Division Publications

2017

  • Qiu GT, Shi ZJ, Xu HHK, Yang B, Weir MD, Li GJ, Song Y, Wang JX, Hu K, Wang P, Zhao L.  Bone regeneration in minipigs via calcium phosphate cement scaffold delivering autologous BMSCs and platelet-rich plasma.  J Tissue Eng Reg Med 2017, doi:10.1002/term.2416.

  • Liu X, Chen WC, Zhang C, Thein-Han WW, Hu K, Reynolds MA, Bao CY, Wang P, Zhao L, Xu HHK.  Co-seeding human endothelial cells with hiPSC-derived mesenchymal stem cells on calcium phosphate scaffold enhances osteogenesis and vascularization in rats.  Tissue Engineering A 2017;23:546-555. 

  • Song Y, Zhang C, Wang P, Wang L, Bao CY, Weir MD, Reynolds MA, Ren K, Zhao L, Xu HHK.  Engineering bone regeneration with novel cell-laden hydrogel microfiber-injectable calcium phosphate scaffold.  Materials Science & Engineering C-Materials for Biological Applications 2017;75:895-905.

  • Zhang C, Hu K, Liu X, Reynolds MA, Wang P, Bao CY, Zhao L, Xu HHK.  Novel hiPSC-based tri-culture for pre-vascularization of calcium phosphate scaffold to enhance bone and vessel formation.  Mater Sci & Eng C 2017;79:296-304. 

  • Liang KN, Zhou H, Weir MD, Bao CY, Reynolds MA, Zhou XD, Li JY, Xu HHK. Poly (amido amine) and calcium phosphate nanocomposite remineralization of dentin in acidic solution without calcium phosphate ions. Dent Mater 2017;33(7):818-829. 

  • Ma YS, Zhang N, Weir MD, Bai YX, Xu HHK. Novel multifunctional dental cement to prevent enamel demineralization near orthodontic brackets. J Dent 64 2017;64:58–67.

  • Cheng L, Zhang K, Zhang N, Melo MAS, Weir MD, Zhou XD, Bai YX, Reynolds MA, Xu HHK.  Development of new generation antimicrobial and bioactive dental resins. J Dent Res 2017;1–9. DOI: 10.1177/0022034517709739.

  • Wang L, Xie XJ, Li CY, Liu HB, Zhang K, Zhou YM, Chang XF, Xu HHK. Novel bioactive root canal sealer to inhibit endodontic multispecies biofilms with remineralizing calcium phosphate ions. Journal of Dentistry 60 (2017) 25–35.

  • Han Q, Li BL, Zhou XD, Ge Y, Wang SP, Li MY, Ren B, Wang HH, Zhang KK, Xu HHK, Peng X, Feng MY, Weir MD, Chen Y, Cheng L.  Anti-caries effects of dental adhesives containing quaternary ammonium methacrylates with different chain lengths.  Materials 2017, 10, 643; doi:10.3390/ma10060643.

  • Wang L, Li CY, Weir MD, Zhang K, Zhou YM, Xu HHK, Reynolds MA.  Novel multifunctional dental bonding agent for class-V restorations to inhibit periodontal biofilms.  RSC Adv 2017, 7, 29004–29014.

  • Xie XJ, Wang L, Xing D, Zhang K, Weir MD, Liu HB, Bai YX, Xu HHK. Novel dental adhesive with triple benefits of calcium phosphate recharge, protein-repellent and antibacterial functions. Dent Mater 2017;33:553–563.

  • Zhang N, Ma YS, Weir MD, Xu HHK, Bai YX, Melo MAS.  Current insights into the modulation of oral bacterial degradation of dental polymeric restorative materials.  Materials 2017, 10, 507; doi: 10.3390/ma10050507.

  • Chen H, Han Q, Zhou XD, Zhang KK, Wang SP, Xu HHK, Weir MD, Feng MY, Li MY, Peng X, Ren B, Cheng L.  Heat-polymerized resin containing dimethylaminododecyl methacrylate inhibits Candida albicans biofilm.  Materials 2017, 10, 431; doi:10.3390/ma10040431.

  • Melo MAS, Weir MD, Passos VF, Powers M, Xu HHK.  pH-activated nano-amorphous calcium phosphate-based cement to reduce dental enamel demineralization.  Artificial Cells, Nanomed Biotech 2017, http://dx.doi.org/10.1080/21691401.2017.1290644.

  • Xiao SM, Liang KN, Weir MD, Cheng L, Liu HB, Zhou XD, Ding Y, Xu HHK.  Combining bioactive multifunctional dental composite with PAMAM for root dentin remineralization. Materials 2017, 10, 89; doi:10.3390/ma10010089. 

  • Zhang N, Zhang K, Melo MAS, Weir MD, Xu DJ, Bai YX, Xu HHK.  Effects of long-term water-aging on novel protein-repellent and antibacterial dental composite.  Int J Mol Sci 2017, 18, 186; doi:10.3390/ijms18010186.

  • Ge Y, Ren B, Zhou XD, Xu HHK, Wang SP, Li MY, Weir MD, Feng MY, Cheng L. Novel dental adhesive with biofilm-regulating and remineralization capabilities. Materials 2017, 10, 26; doi:10.3390/ma10010026.

  • Xie XJ, Xing D, Wang L, Zhou H, Weir MD, Bai YX, Xu HHK.  Novel rechargeable calcium phosphate nanoparticle-containing orthodontic cement.  Int J Oral Sci 2016, doi: 10.1038/ijos.2016.40.

  • Liang K, Weir MD, Reynolds MA, Zhou XD, Li J, Xu HHK. Poly (amido amine) and nano-calcium phosphate bonding agent to remineralize tooth dentin in cyclic artificial saliva/lactic acid. Mater Sci Eng C Mater Biol Appl 2017;72:7-17.

2016

  • Xie XJ, Xing D, Wang L, Zhou H, Weir MD, Bai YX, Xu HHK.  Novel rechargeable calcium phosphate nanoparticle-containing orthodontic cement.  Int J Oral Sci 2016, doi: 10.1038/ijos.2016.40.

  • Liang K, Weir MD, Reynolds MA, Zhou XD, Li J, Xu HHK. Poly (amido amine) and nano-calcium phosphate bonding agent to remineralize tooth dentin in cyclic artificial saliva/lactic acid. Mater Sci Eng C Mater Biol Appl2017;72:7-17.

  • Wang L, Melo MAS, Weir MD, Xie XJ, Reynolds MA, Xu HHK.  Novel bioactive nanocomposite for Class-V restorations to inhibit periodontitis-related pathogens. Dent Mater 2016;32:e351–e361.

  • Chen C, Cheng L, Weir MD, Lin NJ, Lin-Gibson S, Zhou XD, Xu HHK. Primer containing dimethylaminododecyl methacrylate kills bacteria impregnated in human dentin blocks.  Int J Oral Sci 2016;8:239–245.

  • Qiu GT, Wang P, Li GJ, Shi ZJ, Weir MD, Sun JY, Song Y, Wang JX, Xu HHK, Zhao L. Minipig-BMSCs combined with a self-setting calcium phosphate paste for bone tissue engineering. Mol Biotechnol 2016;58:748–756. 

  • Zhou H, Liu HB, Weir MD, Reynolds MA, Zhang K, Xu HHK.  Three-dimensional biofilm properties on dental bonding agent with varying quaternary ammonium charge densities.  Journal of Dentistry 2016;53:73–81.

  • Wang L, Wang P, Weir MD, Reynolds MA, Zhao L, Xu HHK.  Hydrogel fibers encapsulating human stem cells in an injectable calcium phosphate scaffold for bone tissue engineering.  Biomed Mater 2016;11:065008. NIHMSID #: 878980.

  • Wang L, Xie XJ, Weir MD, Fouad AF, Zhao L, Xu HHK.  Effect of bioactive dental adhesive on periodontal and endodontic pathogens.  Journal of Materials Science: Materials in Medicine 2016;27:168, DOI 10.1007/s10856-016-5778-2.

  • Zhang N, Melo MAS, Weir MD, Reynolds MA, Bai YX, Xu HHK.  Do dental resin composites accumulate more oral biofilms and plaque than amalgam and glass ionomer materials?  Materials 2016, 9, 888; doi:10.3390/ma9110888.

  • Liang KN, Weir MD, Xie XJ, Wang L, Reynolds MA, LiJY, Xu HHK.  Dentin remineralization in acid challenge environment via PAMAM and calcium phosphate composite.  Dent Mater 2016;32:1429–1440.

  • Wang L, Zhang C, Li C, Weir MD, Wang P, Mark A. Reynolds MA, Zhao L, Xu HHK.  Injectable calcium phosphate with hydrogel fibers encapsulating induced pluripotent, dental pulp and bone marrow stem cells for bone repair.  Materials Science and Engineering C 2016;69:1125–1136.  NIHMSID #: 878994.

  • Liu X, Bao CY, Xu HHK, Pan J, Hu J, Wang P, Luo E.  Osteoprotegerin gene-modified BMSCs with hydroxyapatite scaffold for treating critical-sized mandibular defects in ovariectomized osteoporotic rats.  Acta Biomaterialia 2016:42:378–388.

  • Zhou W, Ren B, Zhou XD, Xu HHK, Weir MD, Li MY, Feng MY, Li JY, Xu X, Cheng L.  Novel cavity disinfectants containing quaternary ammonium monomer dimethylaminododecyl methacrylate.  Materials 2016, 9, 674; doi:10.3390/ma9080674. 

  • Xie XJ, Wang L, Xing D, Arola DD, Weir MD, Bai YX, Xu HHK.  Protein-repellent and antibacterial functions of a calcium phosphate rechargeable nanocomposite.  Journal of Dentistry 2016;52:15–22. 

  • Wu J, Weir MD, Melo MAS, Strassler HE, Xu HHK.  Effects of water-aging on self-healing dental composite containing microcapsules.  Journal of Dentistry 2016;47:86-93. 

  • Wu JL, Weir MD, Zhang QZhou C, Melo MAS, Xu HHK.  Novel self-healing dental resin with microcapsules of polymerizable triethylene glycol dimethacrylate and N,N-dihydroxyethyl-p-toluidine.  Dental Materials 2016;32:294-304.

  • Wang P, Song Y, Weir MD, Sun J, Zhao L, Simon CG, Xu HHK.  A self-setting iPSMSC-alginate-calcium phosphate paste for bone tissue engineering. Dent Mater 2016;32:252-263. NIHMSID #: 742180.

  • Wang S, Ge Y, Zhou XD, Xu HHK, Weir MD, Zhang K, Wang H, Hannig M, Rupf S, Li Q, Cheng L.  Effect of anti-biofilm glass-ionomer cement on Streptococcus mutans biofilms.  Int J Oral Sci 2016, doi: 10.1038/ijos.2015.55.

  • Cheng L, Zhang K, Zhou C, Weir MD, Zhou XD, Xu HHK.  One-year water-aging of CaP nanocomposite with nano-silver and quaternary ammonium to inhibit oral biofilms and acid production.  Int J Oral Sci, 2016;8:172–181.

  • Zhang KK, Ren B, Zhou XD, Xu HHK, Chen Y, Han Q,  Li B, Weir MD, Li M,  Feng M, Cheng L.  Effect of antimicrobial denture base resin on multi-species biofilm formation.  Int J Mol Sci 2016, 17, 1033; doi:10.3390/ijms17071033.

  • Zhang N, Weir MD, Chen C, Melo MAS, Bai YX, Xu HHK.  Orthodontic cement with protein-repellent and antibacterial properties and the release of calcium and phosphate ions.  J Dent 2016;50:51–59. 

  • Wang L, Xie XJ, Imazato S, Weir MD, Reynolds MA, Xu HHK.  Protein-repellent and antibacterial nanocomposite for Class-V restorations to inhibit periodontitis-related pathogens.  Materials Science and Engineering C: (Materials for Biological Applications2016;67:702-710. 

  • Zhang N, Melo MAS, Antonucci JM, Lin NJ, Lin-Gibson S, Bai YX, Xu HHK.  Novel dental cement to inhibit biofilm growth and acid production for orthodontic applications to avoid enamel demineralization.  Materials 2016, 9, 413; doi:10.3390/ma9060413.

  • Zhang L, Weir MD, Chow LC, Antonucci JM, Chen J, Xu HHK.  Novel rechargeable calcium phosphate dental nanocomposite.  Dent Mater 2016;32:285–293.

  • Zhang K, Cheng L, Weir MD, Bai YX, Xu HHK.  Effects of quaternary ammonium chain length on antibacterial and remineralizing calcium phosphate nanocomposite.  Int J Oral Sci 2016 Mar 30;8:45-53.

  • Zhang N, Zhang K, Melo MAS, Chen C, Fouad AF, Bai YX, Xu HHK.  Novel protein-repellent and biofilm-repellent orthodontic cement containing 2-methacryloyloxyethyl phosphorylcholine.  J Biomed Mater Res Part B 2016;104B:949–959.

  • Melo MAS, Orrego S, Weir MD, Xu HHK, Arola DD.  Designing multiagent dental materials for enhanced resistance to biofilm damage at the bonded interface.  ACS Applied Materials & Interfaces 2016 DOI: 10.1021/acsami.6b01923.  (Impact Factor = 6.723).

2015

  • Wu J, Zhou H, Weir MD, Melo MAS, Levine ED, Xu HHK.  Effect of dimethylaminohexadecyl methacrylate mass fraction on fracture toughness and antibacterial properties of CaP nanocomposite.  Journal of Dentistry 2015;43:1539-1546. 

  • Zhang L, Weir MD, Hack G, Fouad AF, Xu HHK.  Rechargeable dental adhesive with calcium phosphate nanoparticles for long-term ion release to inhibit caries.  J Dent 2015;43:1587–1595.   

  • Zhang N, Weir MD, Bai YX, Xu HHK.  Development of novel dental adhesive with double benefits of protein-repellent and antibacterial capabilities.  Dent Mater 2015 Jul;31(7):845-54.

  • Wu JL, Weir MD, Melo MAS, Xu HHK.  Development of novel self-healing and antibacterial dental composite containing calcium phosphate nanoparticles.  J Dent 2015;43(3):317-26.  

  • Feng J, Cheng L, Zhou X, Xu HHK, Weir MD, Meyer M, Maurer H, Li Q, Hannig M, Rupf S.  In situ antibiofilm effect of glass-ionomer cement containing dimethylaminododecyl methacrylate.  Dent Mater 2015;31(8):992-1002.

  • Zhang KK, Wang SP, Zhou XD, Xu HHK, Weir MD, Ge Y, Wang SD, Cheng L.  Effect of antibacterial dental adhesive on multi-species biofilms formation.  J Dent Res 2015 Apr;94(4):622-9.

  • Cheng L, Zhang K, Weir MD, Melo MAS, Zhou XD, Xu HHK.  Nanotechnology Strategies for Antibacterial and Remineralizing Composites and Adhesives to Tackle Dental Caries.  Nanomedicine 2015;10(4):627–641. (Impact factor = 6.155). 

  • Zhang N, Melo MAS, Chen C, Liu J, Weir MD, Bai Y, Xu HHK.  Development of a multifunctional adhesive system for prevention of root caries and secondary caries.  Dent Mater 2015;31:1119–1131. 

  • Zhang N, Chen C, Melo MAS, Bai YX, Zhou XD, Xu HHK.  A novel protein-repellent dental composite containing 2-methacryloyloxyethyl phosphorylcholine. International J Oral Sci 2015, 1–7.  doi:10.1038/ijos.2014.77.

  • Ge Y, Wang S, Zhou XD, Wang HH, Xu HHK, Cheng L.  The use of quaternary ammonium to combat dental caries.  Materials 2015, 8, 3532-3549; doi:10.3390/ma8063532.  

  • Wang P, Liu X, Zhao L, Weir MD, Sun JR, Chen W, Man Y, Xu HHK.  Bone tissue engineering via human induced pluripotent, umbilical cord and bone marrow mesenchymal stem cells in rat cranium.  Acta Biomaterialia 2015;18:236–248.

  • Li F, Majd H, Weir MD, Arola DD, Xu HHK.  Inhibition of matrix metalloproteinase activity in human dentin via novel antibacterial monomer.  Dent Mater 2015;31:284-292.

  • Zhang N, Ma J, Melo MAS, Weir MD, Bai YX, Xu HHK.  Protein-repellent and antibacterial dental composite to inhibit biofilms and caries.  J Dent 2015;43:225-234.

2014

  • Wang P, Zhao L, Liu J, Weir MD, Zhou XD, Xu HHK.  Bone tissue engineering via nanostructured calcium phosphate biomaterials and stem cells.  Bone Research 2014:2, 14017; doi:10.1038/boneres.2014.17.  

  • Liu J, Chen W, Zhao Z, Xu HHK.  Effect of NELL1 gene overexpression in iPSC-MSCs seeded on calcium phosphate cement.  Acta Biomaterialia 2014;10:5128–5138.  

  • Melo MAS, Wu J, Weir MD, Xu HHK.  Novel antibacterial orthodontic cement containing quaternary ammonium monomer dimethylaminododecyl methacrylate.  J Dent 2014;42:1193 – 1201.

  • Liu X, Wang P, Chen W, Weir MD, Bao C, Xu HHK.  Human embryonic stem cells and macroporous calcium phosphate construct for bone regeneration in cranial defects in rats.   Acta Biomaterialia 2014;10:4484–4493.  

  • Li F, Wang P, Weir MD, Fouad AF, Xu HHK.  Evaluation of novel antibacterial and remineralizing nanocomposite and adhesive in rat tooth cavity model.  Acta Biomaterialia 2014;10:2804–2813.

  • Wang P, Zhao L, Chen W, Liu X, Weir MD, Xu HHK.  Stem cells and calcium phosphate cement scaffolds for bone regeneration.  J Dent Res 2014;93(7):618-625. 

  • Zhang N, Melo MAS, Bai YX, Xu HHK.  Novel protein-repellent dental adhesive containing 2-methacryloyloxyethyl phosphorylcholine. J Dent 2014;42(10):1284-91. 

  • Li F, Weir MD, Xu HHK.  Effect of charge density of bonding agent containing a new quaternary ammonium methacrylate on antibacterial and bonding properties.  Dent Mater 2014;30:433–441.

  • Chen C, Weir MD, Cheng L, Lin NJ, Lin-Gibson S, Chow LC, Zhou X, Xu HHK.  Antibacterial activity and ion release of bonding agent containing amorphous calcium phosphate nanoparticles.  Dent Mater 2014;30:891–901.  

  • Wang S, Zhang K, Zhou X, Xu N, Xu HHK, Weir MD, Ge Y, Wang S, Li M, Li Y, Xu X, Cheng L.  Antibacterial effect of dental adhesive containing dimethylaminododecyl methacrylate on the development of Streptococcus mutans biofilm.  Int J Mol Sci 2014;15(7):12791-12806.  

  • Zhou H, Weir MD, Antonucci JM, Schumacher GE, Zhou X, Xu HHK.  Evaluation of three-dimensional biofilms on antibacterial bonding agents containing novel quaternary ammonium methacrylates.  International J Oral Sci2014;6:77-86.

  • Lee K, Weir MD, Lippens E, Mehta M, Wang P, Duda GN, Kim WS, Mooney DJ, Xu HHK.  Bone regeneration via macroporous CPC in rat critical-sized cranial defects.  Dent Mater 2014;30:e199-e207.  

  • Tang M, Chen W, Liu J, Weir MD, Cheng L, Xu HHK.  Human induced pluripotent stem cell seeding on calcium phosphate scaffold for bone regeneration.  Tissue Eng A 2014;20:1295-1305.  

  • Chen W, Thein-Han W, Weir MD, Xu HHK.  Prevascularization of biofunctional CPC via co-culture for bone engineering.  Dent Mater 2014;30:535-544.  

  • Li F, Liu X, Zhao S, Wu H, Smith AJ, Xu HHK.  Porous chitosan bilayer membrane containing TGF-β1 loaded microspheres for pulp capping and reparative dentin formation in a dog model.  Dent Mater 2014;30:172-181.

  • Li F, Weir MD, Fouad AF, Xu HHK.  Effect of salivary pellicle on antibacterial activity of novel antibacterial dental adhesives using a dental plaque microcosm biofilm model.  Dent Mater 2014;30:182-191.  

  • Liu X, Liao X, Luo E, Bao C, Xu HHK.  Mesenchymal stem cells systemically injected into femoral marrow of dogs home to mandibular defects to enhance new bone formation.  Tissue Eng Part A 2014;20:883-892.

  • Imazato S, Ma S, Chen JH, Xu HHK.  Therapeutic polymers for dental adhesives: Loading resins with bio-active components.  Dent Mater 2014;30:97-104. 

2013

  • Thein-Han W, Liu J, Tang M, Chen W, ChengL, Xu HHK.  Induced pluripotent stem cell-derived mesenchymal stem cell seeding on biofunctionalized calcium phosphate cements.  Bone Res 2013;4:371-384.  

     

  • Melo MAS, Guedes SFF, Xu HHK, Rodrigues LKA.  Nanotechnology-based restorative materials for dental caries management.  Trends in Biotechnology 2013;31:459-67.  Impact Factor = 11.958.  

  • Chen W, Liu J, Manuchehrabadi N, Weir MD, Zhu Z, Xu HHK.  Umbilical cord and bone marrow mesenchymal stem cell seeding on macroporous calcium phosphate for bone regeneration in rat cranial defects.  Biomaterials 2013;34:9917-9925. 

  • Li F, Weir MD, Xu HK.  Effects of quaternary ammonium chain length on antibacterial bonding agents.  J Dent Res 2013;92:932-8.  

  • Zhou H, Li F, Weir MD, Xu HHK.  Dental plaque microcosm response to bonding agents containing quaternary ammonium methacrylates with different chain lengths and charge densities.  J Dent 2013; 41: 1122 - 1131. 

  • Thein-Han W, Xu HHK.  Prevascularization of a gas-foaming macroporous calcium phosphate cement scaffold via coculture of human umbilical vein endothelial cells and osteoblasts.  Tissue Eng A 2013; 19: 1675-85.  

  • Thein-Han WW, Weir MD, Simon CG, Xu HHK.  Non-rigid and tough calcium phosphate cement scaffold seeded with umbilical cord stem cells for bone repair.  J Tissue Eng Regen Med 2013; 7:777–787.  

  • Li F, Weir MD, Fouad AF, Xu HHK.  Time-kill behavior against eight bacterial species and cytotoxicity of novel antibacterial monomers.  J Dent 2013;41:881-891. 

  • Do D, Orrego S, Majd H, Ryou H, Mutluay MM, Xu HHK, Arola D.  Accelerated fatigue of dentin with exposure to lactic acid.  Biomaterials 2013;34:8650-8659.  IF = 7.882. 

  • Zhang K, Li F, Imazato S, Cheng L, Liu H, Arola DD, Bai Y, Xu HHK.  Dual antibacterial agents of nano-silver and 12-methacryloyloxydodecylpyridinium bromide in dental adhesive to inhibit caries.  J Biomed Mater Res B 2013;101:929-38. 

  • Liu J, Chen W, Zhao Z, Xu HHK.  Reprogramming of mesenchymal stem cells derived from iPSCs seeded on biofunctionalized calcium phosphate scaffold for bone engineering.  Biomaterials 2013;34:7862-7872.  IF = 7.882. 

  • Zhou C, Weir MD, Zhang K, Deng D, Cheng L, Xu HHK.  Synthesis of new antibacterial quaternary ammonium monomer for incorporation into CaP nanocomposite.  Dent Mater 2013;29:859-870.  

  • Zhang K, Cheng L, Wu EJ, Weir MD, Bai Y, Xu HHK.  Effect of water-aging on dentin bond strength and anti-biofilm activity of bonding agent containing antibacterial monomer dimethylaminododecyl methacrylate.  J Dent 2013;41:504-513. 

  • Chen W, Zhou H, Weir MD, Tang M, Bao C, Xu HHK.  Human embryonic stem cell seeding on calcium phosphate cement-RGD scaffold for bone repair.  Tissue Engineering A 2013;19:915-927.  

  • Zhang K, Cheng L, Imazato S, Antonucci JM, Lin NJ, Lin-Gibson S, Bai Y, Xu HHK.  Effects of dual antibacterial agents MDPB and nano-silver in primer on microcosm biofilm, cytotoxicity and dentin bond properties.  J Dent 2013;41:464-474.  

  • Melo MAS, Cheng L, Weir MD, Hsia RC, Rodrigues LKA, Xu HHK.  Novel dental adhesive containing antibacterial agents and calcium phosphate nanoparticles.  J Biomed Mater Res Part B: Appl Biomater 2013;101B:620-629. 

  • Cheng L, Zhang K, Weir MD, Liu H, Zhou X, Xu HHK.  Effects of antibacterial primers with quaternary ammonium and nano-silver on S. mutans impregnated in human dentin blocks.  Dent Mater 2013;29:462-472. .

  • Mutluay MM, Zhang K, Ryou H, Yahyazadehfar M, Majd H, Xu HHK, Arola D.  On the fatigue behavior of resin-dentin bonds after degradation by biofilm.  J Mechanical Behavior of Biomed Mater 2013;18:219-231.  

  • Li F, Weir MD, Chen J, Xu HHK.  Comparison of quaternary ammonium-containing with nano-silver-containing adhesive in antibacterial properties and cytotoxicity.  Dent Mater 2013;29:450-461.  

  • Melo MAS, Weir MD, Rodrigues LKA, Xu HHK.  Novel calcium phosphate nanocomposite with caries-inhibition in a human in situ model.  Dent Mater 2013;29:231-240.  

  • Cheng L, Weir MD, Zhang K, Arola DD, Zhou X, Xu HHK.  Dental primer and adhesive containing a new antibacterial quaternary ammonium monomer dimethylaminododecyl methacrylate.  J Dent 2013;41:345-355. 

  • Melo MAS, Cheng L, Zhang K, Weir MD, Rodrigues LKA, Xu HHK.  Novel dental adhesives containing nanoparticles of silver and amorphous calcium phosphate.  Dent Mater 2013;29:199-210.  

  • Song G, Habibovic P, Bao C, Hu J, van Blitterswijk CA, Yuan H, Chen W, Xu HHK.  The homing of bone marrow MSCs to non-osseous sites for ectopic bone formation induced by osteoinductive calcium phosphate.  Biomaterials 2013;34:2167-2176.  

  • Liu J, Xu HHK, Zhou H, Weir MD, Chen Q, Trotman CA.  Human umbilical cord stem cell encapsulation in novel macroporous and injectable fibrin for muscle tissue engineering.  Acta Biomaterialia 2013;9:4688-4697.  

2012

  • Liu J, Zhou H, Weir MD, Xu HHK, Chen Q, Trotman CA.  Fast-degradable microbeads encapsulating human umbilical cord stem cells in alginate for muscle tissue engineering.  Tissue Eng A 2012;18:2303-14.  

  • Zhou H, Chen WC, Weir MD, Xu HHK.  Biofunctionalized calcium phosphate cement to enhance the attachment and osteodifferentiation of stem cells released from fast-degradable alginate-fibrin microbeads.  Tissue Eng Part A 2012;18:1583-95.  

  • Weir MD, Chow LC, Xu HHK.  Remineralization of demineralized enamel via calcium phosphate nanocomposite.  J Dent Res 2012;91:979-984. 

  • Thein-Han W, Xu HHK.  Calcium phosphate cement with biofunctional agents and stem cell seeding for dental and craniofacial bone repair.  Dent Mater 2012;28:1059-1070.  

  • Cheng L, Weir MD, Xu HHK, Antonucci JM, Lin NJ, Lin-Gibson S, Xu SM, Zhou XD.  Effect of amorphous calcium phosphate and silver nanocomposites on dental plaque microcosm biofilms.  J Biomed Mater Res B 2012;100:1378-1386.  

  • Moreau JL, Weir MD, Giuseppetti AA, Chow LC, Antonucci JM, Xu HHK.  Long-term mechanical durability of dental nanocomposites containing amorphous calcium phosphate nanoparticles.  J Biomed Mater Res B 2012:100;1264-1273.  

  • Chen W, Zhou H, Tang M, Weir MD, Bao C, Xu HHK.  Gas-foaming calcium phosphate cement scaffold encapsulating human umbilical cord stem cells.  Tissue Engineering A 2012;18:816-827.  

  • Cheng L, Weir MD, Zhang K, Wu E, Xu SM, Zhou XD, Xu HHK.  Dental plaque microcosm biofilm behavior on calcium phosphate nanocomposite with quaternary ammonium.  Dent Mater 2012;28:853-862.  

  • Zhang K, Melo MAS, Cheng L, Weir MD, Bai YX, Xu HHK.  Effect of quaternary ammonium and silver nanoparticle-containing adhesives on dentin bond strength and dental plaque microcosm biofilms.  Dent Mater 2012;28:842-852.  

  • Tang M, Chen W, Weir MD, Thein-Han W, Xu HHK.  Human embryonic stem cell-encapsulation in alginate microbeads in macroporous calcium phosphate cement for bone tissue engineering.  Acta Biomaterialia 2012;8:3436-3445.  

  • Cheng L, Zhang K, Melo MAS, Weir MD, Zhou XD, Xu HHK.  Anti-biofilm dentin primer with quaternary ammonium and silver nanoparticles.  J Dent Res 2012;91:598-604.  

  • Cheng L, Weir MD, Zhang K, Xu SM, Q Chen, Zhou XD, Xu HHK.  Antibacterial nanocomposite with calcium phosphate and quaternary ammonium.  J Dent Res 2012;91:460-466.  

  • Chen W, Zhou H, Weir MD, Bao C, Xu HHK.  Umbilical cord stem cells released from alginate-fibrin microbeads inside macroporous and biofunctionalized calcium phosphate cement for bone regeneration.  Acta Biomaterialia 2012;8:2297-2306. 

  • Weir MD, Moreau JL, Levine ED, Strassler HD, Chow LC, Xu HHK.  Nanocomposite containing CaF2 nanoparticles: Thermal cycling, wear and long-term water-aging.  Dental Materials 2012;28:642–652.  

  • Cheng L, Weir MD, Limkangwalmongkol P, Hack GD, Xu HHK, Chen QM, Zhou XD.  Tetracalcium phosphate composite containing quaternary ammonium dimethacrylate with antibacterial properties.  J Biomed Mater Res B 2012;100:726-734. 

  • Cheng L, Weir MD, Xu HHK, Antonucci JM, Kraigsley AM, Lin NJ, Lin-Gibson S, Zhou XD.  Antibacterial amorphous calcium phosphate nanocomposite with quaternary ammonium salt and silver nanoparticles.  Dent Mater 2012;28:561-572.  

  • Cheng L, Weir MD, Xu HHK, Kraigsley AM, Lin NJ, Lin-Gibson S, Zhou X.  Antibacterial and physical properties of calcium-phosphate and calcium-fluoride nanocomposites with chlorhexidine.  Dent Mater 2012;28:573-583.  

  • Tang M, Weir MD, Xu HHK.  Mannitol-containing macroporous calcium phosphate cement encapsulating human umbilical cord stem cells.  Journal of Tissue Engineering and Regenerative Medicine 2012;6:214-224.  

2011

  • Thein-Han WW, Xu HHK. Collagen-calcium phosphate cement scaffolds seeded with umbilical cord stem cells for bone tissue engineering. Tissue Eng A 2011;17:2943-2954. NIHMSID #: 331813. PubMed #: 21851269. PMC #: 3226062.
  • Zhou H, Weir MD, Xu HHK. Effect of cell seeding density on proliferation and osteodifferentiation of umbilical cord stem cells on calcium phosphate cement-fiber scaffold. Tissue Eng Part A 2011;17: 2603-2613. NIHMSID #: 331816. PubMed #: 21745111. PMC #: 3204200.
  • Bao C, Chen W, Weir MD, Thein-Han W, Xu HHK. Effects of electrospun submicron fibers in calcium phosphate cement scaffold on mechanical properties and osteogenic differentiation of umbilical cord stem cells. Acta Biomaterialia 2011;7:4037-4044. NIHMSID #: 314017. PubMed #: 21763791. PMC #: 3185192.
  • Moreau JL, Sun L, Chow LC, Xu HHK. Mechanical and acid neutralizing properties and inhibition of bacterial growth of amorphous calcium phosphate dental nanocomposite. J Biomed Mater Res Part B 2011;98:80-88. NIHMSID #: 380806. PubMed #: 21504057. PMC #: 3375606.
  • Zhou H, Xu HHK. The fast release of stem cells from alginate-fibrin microbeads in injectable scaffolds for bone tissue engineering. Biomaterials 2011;32:7503-7513. NIHMSID #: 308519. PubMed #: 21757229. PMC #: 3159408.
  • Zhao L, Tang M, Weir MD, Detamore MS, Xu HHK. Osteogenic media and rhBMP-2 induced differentiation of umbilical cord mesenchymal stem cells encapsulated in alginate microbeads and integrated in an injectable calcium phosphate-chitosan fibrous scaffold. Tissue Engineering Part A 2011;17:969-979. NIHMSID #: 331812. PubMed #: 21091340. PMC #: 3063701.
  • Xu HHK, Moreau JL, Sun L, Chow LC. Nanocomposite containing amorphous calcium phosphate nanoparticles for caries inhibition. Dent Mater 2011;27:762-769. NIHMSID #: 291163. PubMed #: 21514655. PMC #: 3125490.

2010

  • Xu HHK, Zhao L, Weir MD. Stem cell-calcium phosphate constructs for bone engineering. J Dent Res 2010;89:1482-1488.
  • Moreau JL, Xu HHK. Fluoride releasing restorative materials: Effects of pH on mechanical properties and ion release. Dent Mater 2010;26:e227-e235.
  • Xu HHK, Zhao L, Detamore MS, Takagi S, Chow LC. Umbilical cord stem cell seeding on fast-resorbable calcium phosphate bone cement. Tissue Engineering Part A 2010;16:2743-2753.
  • Weir MD, Xu HHK. Human bone marrow stem cell-encapsulating calcium phosphate scaffolds for bone repair. Acta Biomaterialia 2010;6:4118-4126.
  • Zhao L, Weir MD, Xu HHK. An injectable calcium phosphate - alginate hydrogel - umbilical cord mesenchymal stem cell paste for bone tissue engineering. Biomaterials 2010;31:6502-6510.
  • Xu HHK, Moreau JL, Sun L, Chow LC. Novel CaF2 nanocomposite with high strength and F ion release. J Dent Res 2010;89:739-745.
  • Weir MD, Xu HHK. Osteoblastic induction on calcium phosphate cement-chitosan constructs for bone tissue. J Biomed Mater Res A 2010;94A:223–233.
  • Xu HHK, Moreau JL. Dental glass-reinforced composite with calcium and phosphate ion release for caries inhibition. J Biomed Mater Res 2010;92B:332–340.
  • Zhao L, Weir MD, Xu HHK. Human umbilical cord stem cell encapsulation in calcium phosphate scaffolds for bone engineering. Biomaterials 2010;31:3848–3857.
  • Xu HHK, Weir MD, Sun S, Moreau JL, Takagi S, Chow LC, Antonucci JM. Strong nanocomposites with Ca, PO4 and F release for caries inhibition. J Dent Res 2010;89:19-28.
  • Weir MD, Xu HHK. Culture human mesenchymal stem cells with calcium phosphate cement scaffolds for bone repair. J Biomed Mater Res 2010;93B: 93–105.
  • Zhao L, Burguera EF, Xu HHK, Amin N, Ryou H, Arola DD. Fatigue and human umbilical cord stem cell seeding characteristics of calcium phosphate–chitosan–biodegradable fiber scaffolds. Biomaterials 2010;31:840–847.

2009

  • Moreau JL, Xu HHK. Mesenchymal stem cell proliferation and differentiation on an injectable calcium phosphate-chitosan composite scaffold. Biomaterials 2009;30:2675-2682.
  • Xu HHK, Weir MD, Sun L. Calcium and phosphate ion releasing composite: Effect of pH on release and mechanical properties. Dent Mater 2009;25:535-542.
  • Moreau JL, Weir MD, Xu HHK. Self-setting collagen-calcium phosphate bone cement: Mechanical and cellular properties. J Biomed Mater Res A 2009;91:605-613.
  • Xu HHK, Weir MD, Sun L, Ngai S, Takagi S, Chow LC. Effect of filler level and particle size on dental caries-inhibiting Ca-PO4 composite. J Mater Science: Mater in Medicine 2009;20:1771-1779.

2008

  • Xu HHK, Moreau JL, Sun L, Chow LC. Strength and fluoride release characteristics of a calcium fluoride based dental nanocomposite. Biomaterials 2008;29:4261-4267.
  • Xu HHK, Weir MD, Simon CG. Injectable and strong nano-apatite scaffolds for cell/growth factor delivery and bone regeneration. Dental Materials 2008;24:1212-1222.
  • Weir MD, Xu HHK. High-strength, in situ-setting calcium phosphate composite with protein release. J Biomed Mater Res 2008;85A:388-396.
  • Burguera EF, Xu HHK, Sun L. Injectable calcium phosphate cement: Effects of powder-to-liquid ratio and needle size. J Biomed Mater Res 2008;84B:493-502.

2007

  • Xu HHK, Carey LE, Burguera EF. Strong, macroporous, and in situ-setting calcium phosphate cement layered structures. Biomaterials 2007;28:3786-3796.
  • Xu HHK, Weir MD, Sun L, Takagi S, Chow LC. Effect of calcium phosphate nanoparticles on Ca-PO4 composites. J Dent Res 2007;86:378-383.
  • Xu HHK, Carey LE, Simon CG. Macroporous scaffold of premixed calcium phosphate bone cement: Mechanical properties and cell response. J Mater Science: Mater in Medicine 2007;18:1345-1353.
  • Xu HHK, Sun L, Weir MD, Takagi S, Chow LC, Hockey B. Effects of nano-sized monocalcium phosphate monohydrate on Ca-and-PO4-releasing dental composites. J Biomed Mater Res 2007;81B:116-125.
  • Xu HHK, Carey LE, Simon CG Jr, Takagi S, Chow LC. Premixed calcium phosphate cements: synthesis, physical properties, and cell cytotoxicity. Dental Materials 2007;23:433-441.
  • Sun L, Xu HHK, Takagi S, Chow LC. Fast setting CPC-chitosan composite: Mechanical properties and dissolution rates. J Biomater Appl 2007;21:299-315.
  • Xu HHK, Weir MD, Sun L. Dental nanocomposites with Ca-PO4 release: Effects of reinforcement, dicalcium phosphate particle size and silanization. Dental Materials 2007:23:1482-1491.

2006

  • Xu HHK, Weir MD, Burguera EF, Fraser AM. Injectable and macroporous calcium phosphate cement scaffold. Biomaterials 2006;27:4279-4287.
  • Xu HHK, Sun L, Weir MD, Antonucci J, Takagi S, Chow LC. Nano DCPA-whisker composites with high strength and Ca-PO4 release. J Dent Res 2006;85:722-27.
  • Xu HHK, Takagi S, Sun L, Hussain L, Chow LC, Guthrie WF, Yen JH. Calcium phosphate cement with non-rigidity and strength durability for periodontal bone repair. J American Dent Assoc 2006;137:1131-1138.
  • Burguera EF, Xu HHK, Weir MD. Injectable and rapid-setting calcium phosphate bone cement with dicalcium phosphate dihydrate. J Biomed Mater Res 2006;77B:126-134.
  • Weir MD, Xu HHK, Simon CG. Strong calcium phosphate cement-chitosan-mesh construct containing cell-encapsulating hydrogel beads for bone tissue engineering. J Biomed Mater Res 2006;77A:487-496.
  • Zhang Y, Xu HHK, Takagi S, Chow LC. In-situ hardening hydroxyapatite-based scaffold for bone repair. J Mater Science: Mater in Medicine 2006;17:437-445.

2005

  • Xu HHK, Simon CG Jr. Fast setting calcium phosphate-chitosan scaffold: mechanical properties and biocompatibility. Biomaterials 2005;26:1337-1348.
  • Carey LE, Xu HHK, Simon CG, Takagi S, Chow LC. Premixed rapid-setting calcium phosphate composites for bone repair. Biomaterials 2005;26:5002-5014.
  • Xu HHK, Simon CG Jr, Takagi S, Chow LC, Eichmiller FC. Strong, macroporous and in-situ hardening hydroxyapatite for bone tissue engineering. Biomaterials Forum 2005;27:14-19.
  • Burguera EF, Xu HHK, Takagi S, Chow LC. High early-strength calcium phosphate bone cement: Effects of dicalcium phosphate dehydrate and absorbable fibers. J Biomed Mater Res 2005;75A:966-975.
  • Antonucci JM, Dickens SH, Fowler BO, Xu HHK, McNonough WG. Chemistry of silanes: Interfaces in dental polymers and composites. J Res NIST 2005;110:541-558.
  • Zhang Y, Xu HHK. Effects of synergistic reinforcement and absorbable fiber strength on hydroxyapatite bone cement. J Biomed Mater Res 2005;75A:832-840.

2004

  • Xu HHK, Quinn JB, Takagi S, Chow LC. Synergistic reinforcement of in situ hardening calcium phosphate composite scaffold for bone tissue engineering. Biomaterials 2004;25:1029-1037.
  • Xu HHK, Smith DT, Simon CG. Strong and bioactive composites containing nano-silica-fused whiskers for bone repair. Biomaterials 2004;25:4615-4626.
  • Xu HHK, Quinn JB, Giuseppetti AA. Wear and mechanical properties of nano-silica-fused whisker composites. Journal of Dental Research 2004;83:930-935.
  • Xu HHK, Quinn JB, Giuseppetti AA, Eichmiller FC, Parry EE, Schumacher GE. Three-body wear of dental resin composites reinforced with silica-fused whiskers. Dental Materials 2004;20:220-227.
  • Xu HHK, Simon CG. Self-hardening calcium phosphate cement-mesh composite: Reinforcement, macropores, and cell response. J Biomed Mater Res 2004;69A:267-278.
  • Xu HHK, Takagi S, Quinn JB, Chow LC. Fast-setting and anti-washout calcium phosphate scaffolds with high strength and controlled macropore formation rates. J Biomed Mater Res 2004;68A:725-734.
  • Xu HHK, Simon CG. Self-hardening calcium phosphate composite scaffold for bone tissue engineering. Journal of Orthopaedic Research 2004;22:535-543.

2003

  • Xu HHK. Long-term water aging of whisker-reinforced polymer-matrix composites. Journal of Dental Research 2003;82:48-52.
  • Xu HHK, Quinn JB, Smith DT, Giuseppetti AA, Eichmiller FC. Effects of different whiskers on the reinforcement of dental composites. Dent Mater 2003;19:359-367.
  • Xu HHK, Schumacher GE, Eichmiller FC, Peterson RC, Antonucci JM, Mueller HJ. Continuous-fiber preform reinforcement of dental resin composite restorations. Dental Materials 2003;19:523-530.

2002

  • Xu HHK, Quinn JB, Takagi S, Chow LC . Processing and properties of strong and non-rigid calcium phosphate cement. Journal of Dental Research 2002;81:219-224.
  • Xu HHK, Quinn JB. Calcium phosphate cement containing resorbable fibers for short-term reinforcement and macroporosity. Biomaterials 2002;23:193-202.
  • Xu HHK, Eichmiller FC, Smith DT, Schumacher GE, Giuseppetti AA, Antonucci JM. Effect of thermal cycling on whisker-reinforced dental resin composites. J Mater Sci: Mater in Medicine 2002;13:875-883.
  • Xu HHK, Quinn JB, Smith DT, Antonucci JM, Schumacher GE, Eichmiller FC. Dental resin composites containing silica-fused whiskers – Effects of whisker-to-silica ratio on fracture toughness and indentation properties. Biomaterials 2002;23:735-742.

2001

  • Xu HHK, Quinn JB. Effect of silicon carbide whisker-silica heat treatment on the reinforcement of dental resin composites. J Biomed Mater Res 2001;58B:81-87.
  • Xu HHK, Eichmiller FC, Barndt PR. Effects of fiber length and volume fraction on the reinforcement of calcium phosphate cement. J Mater Science: Mater Med 2001;12:57-65.
  • Xu HHK, Quinn JB. Whisker-reinforced bioactive composites containing calcium phosphate cement fillers: Effects of filler ratio and surface treatments on mechanical properties. J Biomed Mater Res 2001;57A:165-174.
  • Xu HHK, Quinn JB, Takagi S, Chow LC, Eichmiller FC. Strong and macroporous calcium phosphate cement: Effects of porosity and fiber reinforcement. J Biomed Mater Res 2001;57A:457-466.

2000

  • Xu HHK. Whisker-reinforced heat-cured dental resin composites: Effects of filler level and heat-cure temperature and time. J Dent Res 2000;79:1392-1397.
  • Xu HHK, Eichmiller FC, Antonucci JM, Schumacher GE, Ives LK. Dental resin composites containing ceramic whiskers and precured glass ionomer particles. Dent Mater 2000;16:356-363.
  • Xu HHK, Schumacher GE, Eichmiller FC, and Antonucci JM. Strengthening composite resin restorations with ceramic whisker reinforcement. Pract Periodont Aesthet Dent 2000;12:111-116.
  • Xu HHK, Eichmiller FC, Antonucci JM, Flaim GM. Single-crystalline ceramic whisker-reinforced carboxylic acid-resin composites with fluoride release. Operative Dentistry 2000;25:90-97.
  • Xu HHK, Smith DT, Schumacher GE, Eichmiller FC, Antonucci JM. Indentation modulus and hardness of whisker-reinforced heat-cured dental resin composites. Dent Mater 2000;16:248-254.
  • Xu HHK, Eichmiller FC, Giuseppetti AA. Reinforcement of a self-setting calcium phosphate cement with different fibers. J Biomed Mater Res 2000;52:107-114.
  • Xu HHK, Smith DT, Schumacher GE, Eichmiller FC. Whisker-reinforced dental core buildup composites: Effect of filler level on mechanical properties. J Biomed Mater Res 2000;52:812-818.
  • Xu HHK, Quinn JB, Giuseppetti AA, Eichmiller FC. Effects of whisker-to-silica ratio on the reinforcement of dental resin composites with silica-fused whiskers. J Dent Res 2000;79:1844-1849.