Publications

  1. Wang S, Nie X, Parastooei G, Kumari S, Abbasi Y, Elnabawi O, Pae EK, Ko CC, Chung MK. Nociceptor Neurons Facilitate Orthodontic Tooth Movement via Piezo2 in Mice. J Dent Res. 2025 Mar 12:220345251317429. doi: 10.1177/00220345251317429. Online ahead of print. PMID: 40071303

  2. Alshanqiti I, Son H, Shannonhouse J, Hu J, Kumari S, Parastooei G, Raman S, Wang S, Ro JY, Kim YS, Chung MK. Posttraumatic hyperalgesia and associated peripheral sensitization after temporomandibular joint injury in mice. Pain. 2024 Dec 17. doi: 10.1097/j.pain.0000000000003498. Online ahead of print. PMID: 39715145 
  3. Son H, Shannonhouse J, Zhang Y, Gomez R, Amarista F, Perez D, Ellis E, Chung MK, Kim YS. Elucidation of neuronal activity in mouse models of temporomandibular joint injury and inflammation by in vivo GCaMP Ca 2+ imaging of intact trigeminal ganglion neurons. Pain. 2024 Dec 1;165(12):2794-2803. doi: 10.1097/j.pain.0000000000003421. Epub 2024 Oct 1. PMID: 39365648
  4. Ali MSS, Parastooei G, Raman S, Mack J, Kim YS, Chung MK. Genetic labeling of the nucleus of tractus solitarius neurons associated with electrical stimulation of the cervical or auricular vagus nerve in mice. Brain Stimul. 2024 Sep-Oct;17(5):987-1000. doi: 10.1016/j.brs.2024.08.007. Epub 2024 Aug 21. PMID: 39173736

  5. Bagues A, Hu J, Alshanqiti I, Chung MK. Neurobiological mechanisms of botulinum neurotoxin-induced analgesia for neuropathic pain. Pharmacol Ther. 2024 Jul;259:108668. doi: 10.1016/j.pharmthera.2024.108668. Epub 2024 May 22. PMID: 38782121

  6. Nie X, Abbasi Y, Chung MK. Piezo1 and Piezo2 collectively regulate jawbone development. Development. 2024 May 1;151(9):dev202386. doi: 10.1242/dev.202386. Epub 2024 May 9. PMID: 38619396
  7. Wang S, Ko CC, Chung MK. Nociceptor mechanisms underlying pain and bone remodeling via orthodontic forces: toward no pain, big gain. Front Pain Res (Lausanne). 2024 Feb 22;5:1365194. doi: 10.3389/fpain.2024.1365194. eCollection 2024. PMID: 38455874
  8. da Silva Fiorin F, do Espírito Santo CC, Da Silva JT, Chung MK. Inflammation, brain connectivity, and neuromodulation in post-traumatic headache. Brain Behav Immun Health. 2024 Jan 6;35:100723. doi: 10.1016/j.bbih.2024.100723. eCollection 2024 Feb. PMID: 38292321
  9. Siddiqui YD, Nie X, Wang S, Abbasi Y, Park L, Fan X, Thumbigere-Math V, Chung MK. Substance P aggravates ligature-induced periodontitis in mice. Front Immunol. 2023 Apr 14;14:1099017. doi: 10.3389/fimmu.2023.1099017. eCollection 2023.
  10. Chung MK, Wang S, Alshanqiti I, Hu J, Ro JY. The degeneration-pain relationship in the temporomandibular joint: Current understandings and rodent models. Front Pain Res (Lausanne). 2023 Feb 9;4:1038808. doi: 10.3389/fpain.2023.1038808. eCollection 2023.

  11. Wang S, Nie X, Siddiqui Y, Wang X, Arora V, Fan X, Thumbigere-Math V, Chung MK. Nociceptor Neurons Magnify Host Responses to Aggravate Periodontitis. J Dent Res. 2022 Jan 27;:220345211069956. doi: 10.1177/00220345211069956. [Epub ahead of print] PubMed PMID: 35086367.

  12. Arora V, Li T, Kumari S, Wang S, Asgar J, Chung MK. Capsaicin-induced depolymerization of axonal microtubules mediates analgesia for trigeminal neuropathic pain. Pain. 2021 Oct 28;. doi: 10.1097/j.pain.0000000000002529. [Epub ahead of print] PubMed PMID: 34724681; PubMed Central PMCID: PMC9046530.
  13. Chung MK, Wang S, Oh SL, Kim YS. Acute and Chronic Pain from Facial Skin and Oral Mucosa: Unique Neurobiology and Challenging Treatment. Int J Mol Sci. 2021 May 28;22(11). doi: 10.3390/ijms22115810. Review. PubMed PMID: 34071720; PubMed Central PMCID: PMC8198570.
  14. Arora V, Campbell JN, Chung MK. Fight fire with fire: Neurobiology of capsaicin-induced analgesia for chronic pain. Pharmacol Ther. 2021 Apr;220:107743. doi: 10.1016/j.pharmthera.2020.107743. Epub 2020 Nov 10. Review. PubMed PMID: 33181192; PubMed Central PMCID: PMC7969397.
  15. Campbell JN, Stevens R, Hanson P, Connolly J, Meske DS, Chung MK, Lascelles BDX. Injectable Capsaicin for the Management of Pain Due to Osteoarthritis. Molecules. 2021 Feb 3;26(4). doi: 10.3390/molecules26040778. Review. PubMed PMID: 33546181; PubMed Central PMCID: PMC7913147.
  16. Chung MK, Wang S, Yang J, Alshanqiti I, Wei F, Ro JY. Neural Pathways of Craniofacial Muscle Pain: Implications for Novel Treatments. J Dent Res. 2020 Aug;99(9):1004-1012. doi: 10.1177/0022034520919384. Epub 2020 May 6. Review. PubMed PMID: 32374638; PubMed Central PMCID: PMC7375738.
  17. Wang S, Bian C, Yang J, Arora V, Gao Y, Wei F, Chung MK. Ablation of TRPV1+ Afferent Terminals by Capsaicin Mediates Long-Lasting Analgesia for Trigeminal Neuropathic Pain. eNeuro. 2020 May/Jun;7(3). doi: 10.1523/ENEURO.0118-20.2020. Print 2020 May/Jun. PubMed PMID: 32404326; PubMed Central PMCID: PMC7266139.
  18. Chung MK, Ro JY. Peripheral glutamate receptor and transient receptor potential channel mechanisms of craniofacial muscle pain. Mol Pain. 2020 Jan-Dec;16:1744806920914204. doi: 10.1177/1744806920914204. Review. PubMed PMID: 32189565; PubMed Central PMCID: PMC7153498.
  19. Wang S, Chung MK. Orthodontic force induces nerve injury-like transcriptomic changes driven by TRPV1-expressing afferents in mouse trigeminal ganglia. Mol Pain. 2020 Jan-Dec;16:1744806920973141. doi: 10.1177/1744806920973141. PubMed PMID: 33215551; PubMed Central PMCID: PMC7686596.
  20. Joseph J, Qu L, Wang S, Kim M, Bennett D, Ro J, Caterina MJ, Chung MK. Phosphorylation of TRPV1 S801 Contributes to Modality-Specific Hyperalgesia in Mice. J Neurosci. 2019 Dec 11;39(50):9954-9966. doi: 10.1523/JNEUROSCI.1064-19.2019. Epub 2019 Nov 1. PubMed PMID: 31676602; PubMed Central PMCID: PMC6978941.
  21. Wang S, Kim M, Ali Z, Ong K, Pae EK, Chung MK. TRPV1 and TRPV1-Expressing Nociceptors Mediate Orofacial Pain Behaviors in a Mouse Model of Orthodontic Tooth Movement. Front Physiol. 2019;10:1207. doi: 10.3389/fphys.2019.01207. eCollection 2019. PubMed PMID: 31620023; PubMed Central PMCID: PMC6763553.
  22. Wang S, Brigoli B, Lim J, Karley A, Chung MK. Roles of TRPV1 and TRPA1 in Spontaneous Pain from Inflamed Masseter Muscle. Neuroscience. 2018 Aug 1;384:290-299. doi: 10.1016/j.neuroscience.2018.05.048. Epub 2018 Jun 8. PubMed PMID: 29890293; PubMed Central PMCID: PMC6086573.
  23. Wang S, Lim J, Joseph J, Wang S, Wei F, Ro JY, Chung MK. Spontaneous and Bite-Evoked Muscle Pain Are Mediated by a Common Nociceptive Pathway With Differential Contribution by TRPV1. J Pain. 2017 Nov;18(11):1333-1345. doi: 10.1016/j.jpain.2017.06.005. Epub 2017 Jun 29. PubMed PMID: 28669862; PubMed Central PMCID: PMC5660653.
  24. Wang S, Wang S, Asgar J, Joseph J, Ro JY, Wei F, Campbell JN, Chung MK. Ca2+ and calpain mediate capsaicin-induced ablation of axonal terminals expressing transient receptor potential vanilloid 1. J Biol Chem. 2017 May 19;292(20):8291-8303. doi: 10.1074/jbc.M117.778290. Epub 2017 Mar 30. PubMed PMID: 28360106; PubMed Central PMCID: PMC5437236.
  25. Chung MK, Campbell JN. Use of Capsaicin to Treat Pain: Mechanistic and Therapeutic Considerations. Pharmaceuticals (Basel). 2016 Nov 1;9(4). doi: 10.3390/ph9040066. Review. PubMed PMID: 27809268; PubMed Central PMCID: PMC5198041.
  26. Chung MK, Park J, Asgar J, Ro JY. Transcriptome analysis of trigeminal ganglia following masseter muscle inflammation in rats. Mol Pain. 2016;12. doi: 10.1177/1744806916668526. Print 2016. PubMed PMID: 27702909; PubMed Central PMCID: PMC5066585.
  27. Wang S, Joseph J, Diatchenko L, Ro JY, Chung MK. Agonist-dependence of functional properties for common nonsynonymous variants of human transient receptor potential vanilloid 1. Pain. 2016 Jul;157(7):1515-1524. doi: 10.1097/j.pain.0000000000000556. PubMed PMID: 26967694; PubMed Central PMCID: PMC5512168.
  28. Wang S, Joseph J, Ro JY, Chung MK. Modality-specific mechanisms of protein kinase C-induced hypersensitivity of TRPV1: S800 is a polymodal sensitization site. Pain. 2015 May;156(5):931-941. doi: 10.1097/j.pain.0000000000000134. PubMed PMID: 25734989; PubMed Central PMCID: PMC4402251.
  29. Joseph J, Wang S, Lee J, Ro JY, Chung MK. Carboxyl-terminal domain of transient receptor potential vanilloid 1 contains distinct segments differentially involved in capsaicin- and heat-induced desensitization. J Biol Chem. 2013 Dec 13;288(50):35690-702. doi: 10.1074/jbc.M113.513374. Epub 2013 Oct 30. PubMed PMID: 24174527; PubMed Central PMCID: PMC3861621.
  30. Huang SM, Chung MK. Targeting TRPV3 for the Development of Novel Analgesics. Open Pain J. 2013;6(Spec Iss 1):119-126. doi: 10.2174/1876386301306010119. PubMed PMID: 25285178; PubMed Central PMCID: PMC4182939.
  31. Chung MK, Jue SS, Dong X. Projection of non-peptidergic afferents to mouse tooth pulp. J Dent Res. 2012 Aug;91(8):777-82. doi: 10.1177/0022034512450298. Epub 2012 Jun 5. PubMed PMID: 22668597; PubMed Central PMCID: PMC3398789.
  32. Wang S, Lee J, Ro JY, Chung MK. Warmth suppresses and desensitizes damage-sensing ion channel TRPA1. Mol Pain. 2012 Mar 29;8:22. doi: 10.1186/1744-8069-8-22. PubMed PMID: 22458587; PubMed Central PMCID: PMC3348001.
  33. Chung MK, Lee J, Duraes G, Ro JY. Lipopolysaccharide-induced pulpitis up-regulates TRPV1 in trigeminal ganglia. J Dent Res. 2011 Sep;90(9):1103-7. doi: 10.1177/0022034511413284. Epub 2011 Jun 28. PubMed PMID: 21712529; PubMed Central PMCID: PMC3169884.
  34. Chung MK, Wang S. Cold suppresses agonist-induced activation of TRPV1. J Dent Res. 2011 Sep;90(9):1098-102. doi: 10.1177/0022034511412074. Epub 2011 Jun 10. PubMed PMID: 21666106; PubMed Central PMCID: PMC3169882.
  35. Chung MK, Jung SJ, Oh SB. Role of TRP channels in pain sensation. Adv Exp Med Biol. 2011;704:615-36. doi: 10.1007/978-94-007-0265-3_33. Review. PubMed PMID: 21290319.