Publications

  1. Wang S, Nie X, Siddiqui Y, Wang X, Arora V, Fan X, Thumbigere-Math V, Chung MK. Nociceptor Neurons Magnify Host Responses to Aggravate Periodontitis. J Dent Res. 2022 Jan 27;:220345211069956. doi: 10.1177/00220345211069956. [Epub ahead of print] PubMed PMID: 35086367.
  2. Arora V, Li T, Kumari S, Wang S, Asgar J, Chung MK. Capsaicin-induced depolymerization of axonal microtubules mediates analgesia for trigeminal neuropathic pain. Pain. 2021 Oct 28;. doi: 10.1097/j.pain.0000000000002529. [Epub ahead of print] PubMed PMID: 34724681; PubMed Central PMCID: PMC9046530.
  3. Chung MK, Wang S, Oh SL, Kim YS. Acute and Chronic Pain from Facial Skin and Oral Mucosa: Unique Neurobiology and Challenging Treatment. Int J Mol Sci. 2021 May 28;22(11). doi: 10.3390/ijms22115810. Review. PubMed PMID: 34071720; PubMed Central PMCID: PMC8198570.
  4. Arora V, Campbell JN, Chung MK. Fight fire with fire: Neurobiology of capsaicin-induced analgesia for chronic pain. Pharmacol Ther. 2021 Apr;220:107743. doi: 10.1016/j.pharmthera.2020.107743. Epub 2020 Nov 10. Review. PubMed PMID: 33181192; PubMed Central PMCID: PMC7969397.
  5. Campbell JN, Stevens R, Hanson P, Connolly J, Meske DS, Chung MK, Lascelles BDX. Injectable Capsaicin for the Management of Pain Due to Osteoarthritis. Molecules. 2021 Feb 3;26(4). doi: 10.3390/molecules26040778. Review. PubMed PMID: 33546181; PubMed Central PMCID: PMC7913147.
  6. Chung MK, Wang S, Yang J, Alshanqiti I, Wei F, Ro JY. Neural Pathways of Craniofacial Muscle Pain: Implications for Novel Treatments. J Dent Res. 2020 Aug;99(9):1004-1012. doi: 10.1177/0022034520919384. Epub 2020 May 6. Review. PubMed PMID: 32374638; PubMed Central PMCID: PMC7375738.
  7. Wang S, Bian C, Yang J, Arora V, Gao Y, Wei F, Chung MK. Ablation of TRPV1+ Afferent Terminals by Capsaicin Mediates Long-Lasting Analgesia for Trigeminal Neuropathic Pain. eNeuro. 2020 May/Jun;7(3). doi: 10.1523/ENEURO.0118-20.2020. Print 2020 May/Jun. PubMed PMID: 32404326; PubMed Central PMCID: PMC7266139.
  8. Chung MK, Ro JY. Peripheral glutamate receptor and transient receptor potential channel mechanisms of craniofacial muscle pain. Mol Pain. 2020 Jan-Dec;16:1744806920914204. doi: 10.1177/1744806920914204. Review. PubMed PMID: 32189565; PubMed Central PMCID: PMC7153498.
  9. Wang S, Chung MK. Orthodontic force induces nerve injury-like transcriptomic changes driven by TRPV1-expressing afferents in mouse trigeminal ganglia. Mol Pain. 2020 Jan-Dec;16:1744806920973141. doi: 10.1177/1744806920973141. PubMed PMID: 33215551; PubMed Central PMCID: PMC7686596.
  10. Joseph J, Qu L, Wang S, Kim M, Bennett D, Ro J, Caterina MJ, Chung MK. Phosphorylation of TRPV1 S801 Contributes to Modality-Specific Hyperalgesia in Mice. J Neurosci. 2019 Dec 11;39(50):9954-9966. doi: 10.1523/JNEUROSCI.1064-19.2019. Epub 2019 Nov 1. PubMed PMID: 31676602; PubMed Central PMCID: PMC6978941.
  11. Wang S, Kim M, Ali Z, Ong K, Pae EK, Chung MK. TRPV1 and TRPV1-Expressing Nociceptors Mediate Orofacial Pain Behaviors in a Mouse Model of Orthodontic Tooth Movement. Front Physiol. 2019;10:1207. doi: 10.3389/fphys.2019.01207. eCollection 2019. PubMed PMID: 31620023; PubMed Central PMCID: PMC6763553.
  12. Wang S, Brigoli B, Lim J, Karley A, Chung MK. Roles of TRPV1 and TRPA1 in Spontaneous Pain from Inflamed Masseter Muscle. Neuroscience. 2018 Aug 1;384:290-299. doi: 10.1016/j.neuroscience.2018.05.048. Epub 2018 Jun 8. PubMed PMID: 29890293; PubMed Central PMCID: PMC6086573.
  13. Wang S, Lim J, Joseph J, Wang S, Wei F, Ro JY, Chung MK. Spontaneous and Bite-Evoked Muscle Pain Are Mediated by a Common Nociceptive Pathway With Differential Contribution by TRPV1. J Pain. 2017 Nov;18(11):1333-1345. doi: 10.1016/j.jpain.2017.06.005. Epub 2017 Jun 29. PubMed PMID: 28669862; PubMed Central PMCID: PMC5660653.
  14. Wang S, Wang S, Asgar J, Joseph J, Ro JY, Wei F, Campbell JN, Chung MK. Ca2+ and calpain mediate capsaicin-induced ablation of axonal terminals expressing transient receptor potential vanilloid 1. J Biol Chem. 2017 May 19;292(20):8291-8303. doi: 10.1074/jbc.M117.778290. Epub 2017 Mar 30. PubMed PMID: 28360106; PubMed Central PMCID: PMC5437236.
  15. Chung MK, Campbell JN. Use of Capsaicin to Treat Pain: Mechanistic and Therapeutic Considerations. Pharmaceuticals (Basel). 2016 Nov 1;9(4). doi: 10.3390/ph9040066. Review. PubMed PMID: 27809268; PubMed Central PMCID: PMC5198041.
  16. Chung MK, Park J, Asgar J, Ro JY. Transcriptome analysis of trigeminal ganglia following masseter muscle inflammation in rats. Mol Pain. 2016;12. doi: 10.1177/1744806916668526. Print 2016. PubMed PMID: 27702909; PubMed Central PMCID: PMC5066585.
  17. Wang S, Joseph J, Diatchenko L, Ro JY, Chung MK. Agonist-dependence of functional properties for common nonsynonymous variants of human transient receptor potential vanilloid 1. Pain. 2016 Jul;157(7):1515-1524. doi: 10.1097/j.pain.0000000000000556. PubMed PMID: 26967694; PubMed Central PMCID: PMC5512168.
  18. Wang S, Joseph J, Ro JY, Chung MK. Modality-specific mechanisms of protein kinase C-induced hypersensitivity of TRPV1: S800 is a polymodal sensitization site. Pain. 2015 May;156(5):931-941. doi: 10.1097/j.pain.0000000000000134. PubMed PMID: 25734989; PubMed Central PMCID: PMC4402251.
  19. Joseph J, Wang S, Lee J, Ro JY, Chung MK. Carboxyl-terminal domain of transient receptor potential vanilloid 1 contains distinct segments differentially involved in capsaicin- and heat-induced desensitization. J Biol Chem. 2013 Dec 13;288(50):35690-702. doi: 10.1074/jbc.M113.513374. Epub 2013 Oct 30. PubMed PMID: 24174527; PubMed Central PMCID: PMC3861621.
  20. Huang SM, Chung MK. Targeting TRPV3 for the Development of Novel Analgesics. Open Pain J. 2013;6(Spec Iss 1):119-126. doi: 10.2174/1876386301306010119. PubMed PMID: 25285178; PubMed Central PMCID: PMC4182939.
  21. Chung MK, Jue SS, Dong X. Projection of non-peptidergic afferents to mouse tooth pulp. J Dent Res. 2012 Aug;91(8):777-82. doi: 10.1177/0022034512450298. Epub 2012 Jun 5. PubMed PMID: 22668597; PubMed Central PMCID: PMC3398789.
  22. Wang S, Lee J, Ro JY, Chung MK. Warmth suppresses and desensitizes damage-sensing ion channel TRPA1. Mol Pain. 2012 Mar 29;8:22. doi: 10.1186/1744-8069-8-22. PubMed PMID: 22458587; PubMed Central PMCID: PMC3348001.
  23. Chung MK, Lee J, Duraes G, Ro JY. Lipopolysaccharide-induced pulpitis up-regulates TRPV1 in trigeminal ganglia. J Dent Res. 2011 Sep;90(9):1103-7. doi: 10.1177/0022034511413284. Epub 2011 Jun 28. PubMed PMID: 21712529; PubMed Central PMCID: PMC3169884.
  24. Chung MK, Wang S. Cold suppresses agonist-induced activation of TRPV1. J Dent Res. 2011 Sep;90(9):1098-102. doi: 10.1177/0022034511412074. Epub 2011 Jun 10. PubMed PMID: 21666106; PubMed Central PMCID: PMC3169882.
  25. Chung MK, Jung SJ, Oh SB. Role of TRP channels in pain sensation. Adv Exp Med Biol. 2011;704:615-36. doi: 10.1007/978-94-007-0265-3_33. Review. PubMed PMID: 21290319.