Publications

Textbooks and Thematic Issues

Shirtliff ME and Leid JG, Editors. Biofilms and Device-Related InfectionsSpringer, New York, NY. 2009. Order from Amazon

Donelli G, Bayston R, Costerton JW, and Shirtliff ME. Eurobiofilms. FEMS Immunol. Med. Micro. 2010.

Peer Reviewed Publications
  • Schlecht LM, Peters BM, Prior ML, Hänsch GM, Filler SG, Jabra-Rizk MA, and Shirtliff ME. Systemic Staphylococcus aureus infection mediated by Candida albicans hyphal invasion in a murine model of oral co-infection. 2012. – submitted to PLoS Pathogens.
  • Peters BM, Ovchinnikova E., Jabra-Rizk MA, Hoyer L, van der Mei HC, Busscher HJ, Krom BP, and Shirtliff ME. Candida albicans hyphal adhesin Als3p mediates interspecies interactions with Staphylococcus aureus during polymicrobial biofilm growth. 2012. – in press. Microbiology.
  • Conti S, Sotereanos N, Altman G, Altman D, Post JC, Ehrlich GD, Gorur A, Schaudinn C, Sedghizadeh P, Shirtliff ME, Costerton JW, Stoodley P, Kathju S, and DeMeo P. Significance of the biofilm mode-of-growth in orthopaedic infections. JBJS. 2012. – in press.
  • O’May GA, Macfarlane S, Macfarlane GT, and Shirtliff ME. Biofilms in the human gastrointestinal tract. 2012. FEMS Immun Med Micro. - in press.
  • Cope E, Cohen N, Dowd SE, Palmer J, Chiu A, Wolcott R, Neeling L, Gmerek A, Smith A, Shirtliff ME, and Leid JG. Primary exposure to cigarette smoke influences microbial community composition in chronic rhinosinusitis determined by next generation pyrosequencing. FEMS Med Micro Immun. 2012. – in press.
  • Ekaterina I. Galanzha EI, Shashkov E, Sarimollaoglu M, Beenken KE, Basnakian A, Kim JW, Shirtliff ME, Smeltzer MS, Zharov VP. In vivo photoacoustic diagnosis and photothermal purging of infected blood using multifunctional nanoparticles. PLoS One. 2012. – in press.
  • Xu Z, Li L, Chu J, Peters BM, Harris ML, Li B, Shi L, Shirtliff ME. Development and application of loop-mediated isothermal amplification assays on rapid detection of various types of staphylococci strains. Food Res Int. 2012 Jul 1;47(2):166-173.
  • Zhu J, Krom BP, Sanglard D, Intapa C, Dawson CC, Peters BM, Shirtliff ME, Jabra-Rizk MA. Farnesol-induced apoptosis in Candida albicans is mediated by Cdr1-p extrusion and depletion of intracellular glutathione. PLoS One. 2011;6(12):e28830. Epub 2011 Dec 19. PMCID:PMC3242750
  • McLean JS, Fansler SJ, Majors PD, McAteer K, Allen LZ, Shirtliff ME, Lux R, and Shi W. Identifying low pH active and lactate-utilizing taxa within oral microbiome communities from healthy children using stable isotope probing techniques. PLoS One. 2012;7(3):e32219.
  • Peters BM, O’May GA, Jabra-Rizk MA, Costerton JW, and Shirtliff ME. Polymicrobial interactions in biofilms: impact on pathogenesis and human disease. Clin Microbiol Rev. 25(1):193-213. 2012.
  • Zhu J, Krom B, Sanglard D, Intapa C, Dawson CC, Peters BM, Shirtliff ME, and Jabra-Rizk MA. Farnesol-induced apoptosis in Candida albicans is mediated by Cdr1-p extrusion and depletion of intracellular glutathione. PLoS One. 2011;6(12):e28830.
  • Cope E, Goldstein-Daruech N, Kofonow J, Christensen L, Gilliland M, McDermott B, Monroy F, Nunamaker J, Palmer J, Chiu A, Shirtliff ME, Cohen N, and Leid JG. Characterization of virulence gene expression resulting from Streptococcus pneumoniae and nontypeable Haemophilus influenzae polymicrobialinteractions in a chronic disease. PLoS One. 6(12):e28523. 2011.
  • Han A, Zenilman JM, Melendez JH, Shirtliff ME, Agostinho A, James G, Stewart PS, Mongodin EF, Rao D, Rickard AH, Lazarus GS. The importance of a multifaceted approach to characterizing the microbial flora of chronic wounds. Wound Repair Regen. 2011 Sep;19(5):532-41. 2011.
  • Xu Z, Lin Li L, Shirtliff ME, Peters BM, Li B, Peng Y, Alam MJ, Yamasaki S, Shi L. Resistance Class 1 Integron in clinical methicillin-resistant Staphylococcus aureus strains in Southern China, 2001-2006. Clin Microbiol Infect. 17(5):714-8, 2011.
  • Prabhakara R, Harro J, Harris M, Leid JG, and Shirtliff ME. Suppression of the inflammatory immune response prevents the development of chronic biofilm infection due to methicillin resistant Staphylococcus aureus. Infect Immun. Epub: Sept 26, 2011.
  • Jacobsen SM and Shirtliff ME. Proteus mirabilis biofilms and catheter-associated urinary tract infections. Virulence. Sep 1;2(5). 2011.
  • Archer NK, Mazaitis MJ, Costerton JW, Leid JG, Powers ME, and Shirtliff ME. Staphylococcus aureus biofilms: Properties, regulation, and roles in human disease. Virulence. Sep 1;2(5), 2011.
  • Prabhakara R, Harro JM, Leid JG, Harris ML, and Shirtliff ME. Murine immune response to a chronic Staphylococcus aureus biofilm infection. Infect Immun. 79(4): 1789-1796, 2011.
  • Brady RA, O’May G, Leid JG, and Shirtliff ME. Resolution of Staphylococcus aureus biofilm infection using vaccination and antibiotic treatment. Infect Immun. 79(4): 1797-1803, 2011.
  • Xu Z, Li L, Shi L, Shirtliff ME. Class 1 integron in staphylococci. Mol Biol Rep. Published online: Jan 22, 2011.
  • Peters BM, Shirtliff ME, Jabra-Rizk MA. Antimicrobial peptides: primeval molecules or future drugs? PLoS Pathog. 2010. 28;6(10):e1001067.
  • Zhao X, Wang L, Chu J, Li Y, Li Y, Xu Z, Li L, Shirtliff ME, He X, Liu Y, Wang J, and Yang L. Rapid detection of Vibrio parahaemolyticus strains and virulent factors by loop-mediated isothermal amplification assays. Food Sci Biotechnol. 2010. 19(5):1191-1197.
  • Xu Z, Li L, Shirtliff ME, Peters BM, Peng Y, Alam MJ, Yamasaki S, Shi L. First report of class 2 integron in clinical Enterococcus faecalis and class 1 integron in Enterococcus faecium in South China. Diagn Microbiol Infect Dis. 2010. 68(3):315-7.
  • Miclau T, Schmidt AH, Wenke JC, Webb LX, Harro JM, Prabhakara R, Shirtliff ME. Infection. J Orthop Trauma. 2010 Sep;24(9):583-6.
  • Donelli G, Bayston R, Costerton WB, Shirtliff ME. The first European congress on microbial biofilms: EUROBIOFILMS 2009, Rome, Italy, September 2-5, 2009. FEMS Immunol Med Microbiol. 2010. 59(3):223-6.
  • Peters BM, Jabra-Rizk MA, Scheper MA, Leid JG, Costerton JW, Shirtliff ME. Microbial interactions and differential protein expression in Staphylococcus aureus -Candida albicans dual-species biofilms. FEMS Immunol Med Microbiol. 2010. 59(3):493-503.
  • Harro JM, Peters BM, O'May GA, Archer N, Kerns P, Prabhakara R, Shirtliff ME. Vaccine development in Staphylococcus aureus: taking the biofilm phenotype into consideration. FEMS Immunol Med Microbiol. 2010. 59(3):306-23.
  • Calhoun JH, Manning M, and Shirtliff ME. Osteomyelitis of the long bones. Sem. Plastic Surg. 23(2):59-72. 2009.
  • Shirtliff ME, Peters B, Jabra-Rizk MA. Cross-kingdom interactions: Candida albicans and Bacteria. FEMS Microbiol Lett. 299(1): 1-8, 2009.
  • Unnanuntana A, Bonsignore L, Shirtliff ME, and Greenfield EM. The effects of farnesol on Staphylococcus aureus biofilms and osteoblasts. An in vitro study. J Bone Joint Surg Am.;(91):2683-92, 2009.
  • Leid JG, Kerr M, Selgado C, Johnson C, Moreno G, Shirtliff ME, O’Toole GA, and Cope EK. Flagellar-mediated biofilm defense mechanisms of Pseudomonas aeruginosa against host derived lactoferrin. J of Immunology. 77(10):4559-66, 2009.
  • Shirtliff ME, Krom BP, Peters B, Zhu J, and Jabra-Rizk MA. Farnesol-induced modifications in Candida albicans proteome. Antimicrob Agents Chemother. 53(6):2392-401, 2009.
  • O’May G, Jacobsen SM, Mobley H, and Shirtliff ME. The high-affinity phosphate transporter Pst in Proteus mirabilis HI4320 and its importance in biofilm formation. Microbiology. 155(5):1547-1557, 2009.
  • Meiller TF, Hube B, Schild L, Shirtliff ME, Scheper MA, Ton A, and Jabra-Rizk MA. A novel immune evasion strategy of Candida albicans: proteolytic cleavage of a salivary antimicrobial peptide. PLoS ONE. 4(4):e5039, 1-9, 2009.
  • Xu Z, Li L, Shirtliff ME, Alam MJ, Yamasaki S, Shi L. Occurrence and characteristics of class 1 and 2 integrons in Pseudomonas aeruginosa isolates from patients in southern China. J Clin Microbiol. 47(1):230-4, 2009.
  • Scheper MA, Shirtliff ME, Meiller TF, Peters B, and Jabra-Rizk MA. Farnesol a fungal quorum sensing molecule triggers apoptosis in human oral squamous carcinoma cells. Neoplasia. 10(9):954-63, 2008.
  • Jacobsen SM, Lane MC, Harro JM, Shirtliff ME*, and Mobley HLT*. *Both authors contributed equally. The high-affinity phosphate transporter Pst is a virulence factor for Proteus mirabilis during complicated urinary tract infection. FEMS Immun Med Micro. 52(2):180-93, 2008.
  • Jacobsen SM, Stickler D, Mobley HLT, and Shirtliff ME. The role of Escherichia coli and Proteus mirabilis in catheter-related urinary tract infections. Clin Micro Rev. 21(1):26-59, 2008.
  • Brady R, Leid JG, Calhoun JH, and Shirtliff ME. Osteomyelitis and the role of biofilms in chronic infection. FEMS Immun Med Micro. 52:13-22, 2008.
  • Brady RA, Leid JG, Kofonow J, Costerton JW, and Shirtliff ME. Immunoglobulins to surface-associated biofilm immunogens provide a novel means of visualization of methicillin-resistant Staphylococcus aureus biofilms. Appl Env Micro. 73(20): class="pages"6612-9, 2007.
  • Lazzarini L, Overgaard KA, Conti E, and Shirtliff ME. Experimental osteomyelitis: what have we learned from animal studies about the systemic treatment of osteomyelitis? J Chemother. 18(5): 451-460, 2006.
  • Jabra-Rizk MA, Shirtliff M, James C, and Meiller T. Farnesol effect on Candida albicans and Candida dubliensis. FEMS Yeast Research. 6(7):1063-73, 2006.
  • Brady RA, Leid JG, Costerton JW, and Shirtliff ME. Identification of Staphylococcus aureus proteins recognized by the antibody mediated immune response to a biofilm infection. Infect Immun. 74(6): 3415-3426, 2006.
  • Jabra-Rizk MA, Meiller T, James CE, and Shirtliff ME. Effect of farnesol on Staphylococcus aureus biofilm formation and antimicrobial susceptibility. Antimicrob Agents Chemother. 50(4):1463-9 2006.
  • Brady RA, Leid JG, Costerton JW, and Shirtliff ME. Osteomyelitis. Clin Micro News. 28(9): 65-72, 2006.
  • Leid JG, Carey JW, Shirtliff ME, Hassett DJ, Parsek MR, and Jeffers AK. The exopolysaccharide alginate protects Pseudomonas aeruginosa biofilm bacteria from IFN-g-mediated macrophage killing. J Imm. 175(11):7512-8, 2005.
  • Shirtliff ME, Bargmeyer A, and Camper AK. Assessment of the bioelectric effect to eliminate mixed water species biofilms. Appl Environ Micro.71(10):6379-82, 2005.
  • Fux CA, Shirtliff ME, Stoodley P, and Costerton JW. Can laboratory strains mirror “real world” pathogenesis? Trends Micro. 13(2):2005.
  • Bargmeyer A, Shirtliff M, Butterfield P, Camper A, Friedman M, and Boyd G. Innovative Biofilm Prevention Strategies. AWWARF Report 91011F. IWA Publishing. June, 2005.
  • Costerton JW, Veeh R, Shirtliff ME, Pasmore M, Post C, and Ehrlich G. The application of biofilm science to the study and control of chronic bacterial infections. J Clin Invest. 112(10):1466-1477, 2003.
  • Worley SD, Li F, Wu R, Wei C-I, Williams JF, Owens J, Wander JD, Bargmeyer AM, and Shirtliff ME. A novel N-halamine monomer for preparing biocidal polyurethane coatings. Surface Coatings Int. Part B: Coat. Trans. 86(B4):273-277, 2003.
  • Shirtliff ME and Mader JT. Imaging in osteomyelitis. Curr Treat Options Infect Dis 5(4):323-335, 2003.
  • Veeh RH, Shirtliff ME, Petik JR, Flood JA, Davis CC, Seymour JL, Hannsmen MA, Kerr KM, Costerton JW, and Pasmore, M. Detection of Staphylococcus aureus biofilm on tampons and menses. J Infect Dis. 188(4):519-530, 2003.
  • Shirtliff ME, Mader JT, and Camper AK. Molecular interactions in biofilms. Chem and Biol. 9(8):859-865, 2002.
  • Shirtliff ME and Mader JT. Acute septic arthritis. Clin Micro Rev. 15(4):527-544, 2002.
  • Chen JJ, Huang JC, Shirtliff M, Briscoe E, Ali S, Cesani F, Paar D, Cloyd MW. CD4 lymphocytes in the blood of HIV(+) individuals migrate rapidly to lymph nodes and bone marrow: support for homing theory of CD4 cell depletion. J Leukoc Biol. 72(2):271-8, 2002
  • Leid JG, Costerton JW, Shirtliff ME, Gilmore MS, and Engelbert M. Immunology of staphylococcal biofilm infections in the eye: New tools to study endophthalmitis. J DNA Cell Biol. 21(5):405-413, 2002.
  • Shirtliff ME, Calhoun JH, and Mader JT. Experimental osteomyelitis treatment with antibiotic-impregnated hydroxyapatite. Clin Orth Related Res. 401:239-247, 2002.
  • Leid JG, Shirtliff ME, Costerton JW, and Stoodley P. Human leukocytes adhere to, penetrate, and respond to S. aureus biofilms. Infect Immun. 70(11): 6339-6345, 2002.
  • Shirtliff ME, Calhoun JH, and Mader JT. Evaluation of gatifloxacin in the treatment of methicillin sensitive S. aureus osteomyelitis in a rabbit model. Antimicrob Agents Chemother. 46(1):231-233, 2002.
  • Shirtliff ME, Calhoun JH, and Mader JT. The treatment of experimental methicillin sensitive S. aureus osteomyelitis in rabbits with levofloxacin and nafcillin. J Antimicrobial Chemother. 48(2):253-258, 2001.
  • Balaban N, Collins LV, Cullor JS, Hume EB, Medina-Acosta E, Vieira da Motta O, O'Callaghan R, Rossitto PV, Shirtliff ME, Serafim da Silveira L, Tarkowski A, and Torres JV. Prevention of diseases caused by Staphylococcus aureus using the peptide RIP. Peptides. 21(9):1301-1311, 2000.
  • Mader JT, Shirtliff ME, Bergquist S, and Calhoun JH. Bone and joint infections in the elderly. Practical treatment guidelines. Drugs & Aging. 10(1):1170-1185, 2000.
  • Mader JT, Shirtliff ME, Bergquist S, and Calhoun JH. Antimicrobial treatment of chronic osteomyelitis. Clin Orth Related Res. 360:47-65, 1999.
  • Shirtliff ME, Calhoun JH, and Mader JT. Rifampin plus azithromycin or clarithromycin to treat osteomyelitis in rabbits. Clin Orth Related Res. 359:229-236, 1999.
  • Ali SA, Cesani F, Nusynowitz ML, Briscoe EG, Shirtliff ME, Mader JT. Skeletal scintigraphy with technetium-99m-tetraphenyl porphyrin sulfonate for the detection and determination of osteomyelitis in an animal model. J Nuc Med. 38(12):1999-2002, 1997.
  • Mader JT, Shirtliff ME, and Calhoun JH. Staging and staging application in osteomyelitis. Clin Infect Dis. 25(6):1303-1309, 1997.
  • Davis CP, Shirtliff ME, Scimeca JM, Hoskins SL, and Warren MM. In vivo reduction of bacterial populations in the urinary tract of catheterized sheep by iontophoresis. J Urol. 154:1948-53, 1995.
  • Davis CP, Shirtliff ME, Trieff NM, Hoskins SL, and Warren MM. Quantification, qualification, and microbial killing efficiencies of antimicrobial chlorine-based substances produced by iontophoresis. Antimicrob Agents Chemother. 38:2768-74, 1994.

Book Chapters

  • Stoodley P, Hall-Stoodley L, Costerton JW, DeMeo P, Shirtliff ME, Gawalt E, and Kathju S. Biofilms, Biomaterials, and Device-Related Infections. In Biomaterials. 2011. – in press.
  • Leid JG, Cope EK, Parmenter S, Shirtliff ME, Dowd S, Wolcott R, Basaraba R, Hunsaker H, Palmer J, and Cohen N. The importance of biofilms in chronic rhinosinusitis. Biofilm Infections. Springer Inc. New York, New York. 2010. 139-160.
  • O’May GA, Brady RA, Leid JG, Calhoun JH, and Shirtliff ME. Osteomyelitis. Biofilm Infections. Springer Inc. New York, New York. 2010. 111-138.
  • Brady RA, Calhoun JH, Leid JG, and Shirtliff ME. Infections of orthopaedic implants and devices. In: Biofilms and Device-Related Infections. Springer, New York, NY. ed. Shirtliff ME and Leid JG. 15-56, 2009.
  • Costerton JW, Veeh R, Shirtliff ME, Pasmore M, Post C, and Ehlich G. The application of biofilm science to the study and control of chronic bacterial infections. In: Science in Medicine: The JCI Textbook of Molecular Medicine. ed Marks AR. American Society for Clinical Investigation. Jones and Bartlett, Boston, MA. 121-131, 2009.
  • O’May G, Jacobsen SM, Mobley H, and Shirtliff ME. Catheter-related urinary tract infections. In: Biofilms and Device-Related Infections. Springer, New York, NY. ed. Shirtliff ME and Leid JG. 123-166, 2009.
  • M. Nymer M, Cope E, Brady R, Shirtliff ME, and Leid JG. Immune responses to indwelling medical devices. In: Biofilms and Device-Related Infections. Springer, New York, NY. ed. Shirtliff ME and Leid JG. 239-264, 2009.
  • Fux CA, Stoodley P, Shirtliff ME, and Costerton JW. Biofilms. In: Antimicrobial Drug Resistance: Principles and Practice for the Clinic and Bench. ed Mayers DL. Infectious Disease Series. ed Georgiev VS. Humana Press. March, 2008.
  • Calhoun JH, Sexton DJ, and Shirtliff ME. Hematogenous osteomyelitis in adults. In: Infectious Diseases. Up To Date Publishing Corporation. Wellesley, MA. 2007.
  • Calhoun J, Christensen G, Brady RA, Shirtliff ME. Osteomyelitis. In: Expert Guide to Infectious Diseases. ed. Tan JS. American College of Physicians-American Society of Internal Medicine. Philadelphia, PA. 2007.
  • Shirtliff ME, Singh Bal B, Yin L, and Calhoun JH. Staging systems for long bone osteomyelitis. In: Infectious Diseases. Up To Date Publishing Corporation. Wellesley, MA. 2006.
  • Shirtliff ME, Cripps MW, and Calhoun JH. Staging systems for long bone osteomyelitis. In: Infectious Diseases. Up To Date Publishing Corporation. Wellesley, MA. 2005.
  • Costerton JW, Stoodley P, Shirtliff ME, Pasmore M, Cook G. Biofilms, biomaterials, and device-related infections. In: Biomaterials Science: An Introduction to Materials in Medicine. ed. Ratner BD, Hoffman AS, Schoen FJ, and Lemons JE., Elsevier Academic Press. 345-354, 2004.
  • Shirtliff ME, Leid J, and Costerton JW. Basic science of musculoskeletal infections. In: Musculoskeletal Infections. ed. Mader JT and Calhoun JH. Marcel Dekker, Inc. New York, NY. 1-61, 2002.
  • Shirtliff ME and Lefrock J. Septic Arthritis. In: Musculoskeletal Infections. ed. Mader JT and Calhoun JH. Marcel Dekker, Inc. New York, NY. 183-209, 2002.
  • Mader JT and Shirtliff ME. Osteomyelitis. In: Conn's Current Therapy, 2002 Edition. ed. Rakel RE and Bope ET. WB Saunders Co. Philadelphia, PA. 1010-1016, 2002.
  • Mader JT, Wang J, Shirtliff ME, and Calhoun J. Osteomyelitis. Expert Guide to Infectious Diseases. ed. Tan JS. American College of Physicians-American Society of Internal Medicine. Philadelphia, PA. 585-604, 2002.
  • Mader JT, Trevino SG, Galbraith JW, and Shirtliff ME. Osteomyelitis. In: Internal Medicine Pearls, 2nd Edition. ed. Heffner JE and Sahn SA. Hanley & Belfus, Inc. Philadelphia, PA. 191-195, 2001.
  • Shirtliff ME and Mader JT. Osteomyelitis: Clinical Features and Molecular Aspects of Persistence. In: Persistent Bacterial Infections. ed. Nataro JP, Blaser MJ, and Cunningham-Rundles S. ASM Press, Washington DC. 375-395, 2000.
  • Mader JT and Shirtliff ME. The Rabbit Model of Bacterial Osteomyelitis of the Tibia. In: Handbook of Animal Models of Infection. ed. Zak O and Sande MA. Academic Press Ltd. London, England. 581–591, 1999.
  • Mader JT, Shirtliff ME, and Calhoun JH. Practical guidelines in the diagnosis and treatment of osteomyelitis. In: Infectious Diseases. Up To Date Publishing Corporation. Wellesley, MA. 1999.
  • Mader JT, Shirtliff ME, Bergquist S, and Calhoun JH. Principles of management and treatment of osteomyelitis. In: Infectious Diseases. Up To Date Publishing Corporation. Wellesley, MA. 1999.
  • Mader JT, Shirtliff ME, and Calhoun JH. The host and the skeletal infection: Classification and pathogenesis of acute bacterial bone and joint sepsis. In: Baillière's Best Practice & Research. Clinical Rheumatology. ed. Woolf AD. 13(1):1-20, 1999.
  • Mader JT, Shirtliff ME, and Calhoun JH. The use of hyperbaric oxygen in the treatment of osteomyelitis. In: Hyperbaric Medicine Practice. Best Publishing Co. Flagstaff, Arizona. 603-616, 1999.
  • Mader JT, Shirtliff ME, Cripps MW, and Calhoun JH. Staging systems for long bone osteomyelitis. In: Infectious Diseases. Up To Date Publishing Corporation. Wellesley, MA. 1998.
  • Mader JT, Shirtliff ME, Cripps MW, and Calhoun JH. Cierny-Mader staging and the treatment of long bone osteomyelitis. In: Infectious Diseases. Up To Date Publishing Corporation. Wellesley, MA. 1998.