Core Imaging Facility provides a wide range of electron microscopy related research services. All services are available to anyone, academic or private users, with an interest in electron microscopy.
- Conventional TEM sample preparation including embedding in various types of resin and ultrathin sectioning.
- Conventional SEM sample preparation including chemical dehydration, critical point drying and sputter coating.
- Immuno electron microscopy including pre-embedding, post embedding or Tokuyasu immunolabeling methods.
- Negative staining of purified macromolecular complexes, bacteria, viruses, liposomes, nanoparticles, or viral like particles (VLP).
- Cryo-sample preparation for both TEM and SEM including high pressure freezing, freeze substitution, cryo-ultramicrotomy, plunge freezing and freeze fracture.
- Advanced microscopy techniques, such as cryoEM, correlative LM/EM and 3D EM for pilot studies.
- Electron microscopes imaging for trained or novice users.
- Supporting equipment usage, EMCIF is equipped with several stereo microscopes with digital cameras, one inverted and one upright fluorescence microscope with capabilities for bright field and epi-fluorescence imaging, three ultramicrotomes, one sputter coater/carbon evaporator, one glow-discharger, one automated EM Specimen processor. Please check Equipment page for details of each instrument.
- Education, consultation and training.
We strive to treat every project individually and optimize for each project's specific requirement.