Endodontics, Prosthodontics and Operative Dentistry

Grants

Primary and Therapy-Resistant Endodontic Infections. National Institute of Dental and Craniofacial Research-NIH (R01-DE015320-01A1)(2005-2009) Fouad, AF Principal Investigator.  

American College of Prosthodontics/Proctor and Gamble  “The Change in Retentive Values of Locator Attachments and Hader Clips  Over Time” 2005-2007 Driscoll, CF Co-investigator                      

Comparison of Electric and Air Driven Handpieces on the Sectioning of Various Restorative Materials, 2005-2006. American Academy of Fixed Prosthodontics (Tylman Grant). Driscoll, CF Principal Investigator

Radiographic Evaluation of All Ceramic Margins, 2005-2006, American Academy of Fixed Prosthodontics (Tylman Grant).  Driscoll, CF Principal Investigator

Pulp tissue engineering  GT.-J. Huang (P.I.),  Songtao Shi, Bruce Rutherford Funding agent: American Association of Endodontists Foundation. 2006-2007

A novel herpesviral vector for oral gene delivery Hongyu Deng, GT.-J. Huang PHS/NIDCR (National Institute of Dental Craniofacial Research)Type: K22 (2004-2009)

Clinical Evaluation of Tagatose Using a Four-Day Plaque Regrowth Model Phase I. BioSpherix, Principal Investigator, (February 2005 – March 2006). completed Litkowski, LJ

Evaluation of Remina Technology for the Stabilization and Remineralization of Teeth, Oramin, Inc. Principal Investigator, (February 2005 – February 2006). Deferred to Fall 2006, Litkowski, LJ

Comparison of Oxycodone/Ibuprofen Combination to Oxycodone/Aspirin and Hydrocodone/acetaminaphen for the Reduction of Post-extraction Pain. Forest Laboratories, Principal Investigator, (March 2004 – December 2005). completed, Litkowski, LJ

Long Term Open Label Multicenter Phase III Trial of Safety and Efficacy of Minocycline Periodontal Therapeutic System (Minocycline PTS) Adjunctive use in Patients with Adult Periodontitis, OraPharma, Inc. Co-Investigator, (January 2004 – January 2006). completed, Litkowski, LJ

Surface Characteristics of Tooth Enamel Chips: in situ Study, Church & Dwight Company, Principal Investigator  (December 2002 – December 2005) Extended with increase in funding December 2006, Litkowski, LJ
 
Clinical Evaluation of Naturlose in a Six Month Gingivitis Trial BioSpherix, Principal Investigator, (March 2006 – December 2007). Litkowski, LJ
 
Clinical Evaluation of  Periocline in patients with moderate to severe Periodontitis, Sunstar- Butler, Principal Investigator, (July 2005 – December 2007). Litkowski, LJ

Clinical Outcomes of splinted and Individual 8 mm Implant restorations following Immediate or delayed loading in the posterior mandible, 2006-415. Nobel Biocare. Armellini, DB

Are endodontic infections involved in the pathogenesis of atherosclerosis? American Association of Endodontists Foundation. R. Mirchandani, A. Fouad

An In Vitro Investigation of the Influence of Age, Root Morphology, Dentin Thickness and Tubular Orientation on the Incidence Vertical Root Fractures. American Association of Endodontists Foundation. A. Mireku, A. Fouad, D. Arola

Mechanotransducers in Human Pulpal Afferents. American Association of Endodontists Foundation. J. Melamed, A. Fouad, M. Gold

“CAREER: Aging, Tooth Fracture and the success of Restorative Dentistry” National Science Foundation (NSF), P.I., Arola, D.

 “Development of Apatite Jet Treatments for Human Enamel: A New Tool for General Dentistry”, Technology Development Corporation (TEDCO), Maryland, P.I., Arola, D.

“Acquisition of a Nanoindenter for Exploratory Research on Biological and Engineering Materials”, National Science Foundation: Major Research Instrumentation, P.I. (co-PIs D. Bennet, R. Ma, L.D.T. Topoleski, M. Zupan), Arola, D.

Publications

Fouad AF, Zerella J, Barry J, Spangberg LS. Molecular detection of Enterococcus spp. in root canals of therapy-resistant endodontic infections.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 99(1): 112-118.

Jung IY, Seo MA, Fouad AF, Lee SJ, Kim HJ, Kum KY. Apical anatomy in mesial and mesiobuccal roots of permanent first molars.
J Endod; 31(5):264-8.

Fouad AF, Barry J. The effect of antibiotics and endodontic antimicrobials on the polymerase chain reaction.
J Endod; 31(7)510-13.

Shabahang S, Bakland, L, D’Addario M, Fayad M, Fouad AF, Goodacre C, Hargreaves K, Holland GR, Ingle J, Johnson B, Kuttler S, Lilly J, Loushine R, Mickel A, Newton CW, Rotstein I, Ruddle C, Steffel CL, Torabinejad M.
State of the Art and Science of Endodontics JADA; 136:41-52.

Kaufman B, Spangberg LS, Barry J, Fouad AF. Enterococcus spp. in endodontically treated teeth with and without periradicular lesions.
J Endod; 31(12): 851-6.

Zerella JA, Fouad AF, Spångberg LSW. The effectiveness of a mixture of Calcium Hydroxide and Chlorhexidine Digluconate as a disinfectant during retreatment of failed endodontic cases.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 100(6): 756-61

Habib, BH; von Fraunhofer, JA; Driscoll, CF: Comparison of Two Luting Agents Used for the Retention of Cast Dowels and Cores. 
J Prosthodont. 14: 164-169.

Masri R, Ro J, Capra N. Effect of algesic chemical stimulation on jaw muscle spindle afferent sensitivity.
Brain Res. Jul 19:138-47.

Litkowski, LJ, Christensen, SE, Adamson, DN, Van Dyke, T, Han, SH & Newman, K: Analgesic Efficacy and Tolerability of Oxycodone 5mg/Ibuprofen 400mg Compared with Oxycodone 5mg/Acetaminophen 325 mg and Hydrocodone 7.5mg/Acetaminophen 500 mg in Patients with Moderate to Severe Postoperative Pain: A Randomized, Double-Blind, Placebo-Controlled, Single Dose, Parallel-Group Study in a Dental Pain Model.
Clinical Therapeutics 27(4):1-12.

D. Armellini, R. Carmichael , John Daskalogiannakis , J. A. von Fraunhofer; Camouflaging Changes in the Appearance of a Patient with Ectodermal Dysplasia.
J Implant Dentistry;14;1-6.

Masri R, Ro J, Dessem D, Capra N. Classification of muscle spindle afferents innervating  the masseter muscle in rats.
Arch Oral  Bio. (In press).

Dersley G, Masri R. A technique to recement provisional crowns by reactivating residual zinc oxide-eugenol cement.
J Prosthet Dent. J Prosthet Dent. 2006 May;95(5):397-8

Varghese R, Masri R, Driscoll CF, Romberg E. The effect of denture cleansing solutions on the retention of yellow Hader clips; an In-Vitro study.
J Prosthodont. (In press).

Al-Ahmad, Masri R, Driscoll CF, von Fraunhofer, JA, Romberg E. Pressure generated on a mandibular simulated oral analog by impression materials in custom trays of different designs.
J Prosthodont. 2006 Mar-Apr;15(2):95-101.

D. Armellini, S. Bilko, R. Carmichael, J. A. von Fraunhofer.Screw-retained prosthesis for Straumann implant sites of limited interocclusal height
J Prosthdont;15:198-201

Park, S; Driscoll, CF; Romberg, E; Siegel, S; Thompson, GA: Ceramic Implant Abutments: Cutting Efficiency and Resultant Surface Finish.
J Prosthet Dent. 2006 Jun;95(6):444-9. 

Berger, JC; Driscoll, CF: Rehabilitation of a Spark Erosion Prosthesis. 
J Prosthodont. 2006 Mar-Apr;15(2):113-6. 

Berger, JC; Driscoll, CF; Romberg E; Luo, Q; Thompson, GA:Surface Roughness of Denture Base Acrylic Resins After Processing and After Polishing.
J Prosthodont. 2006 May-Jun;15(3):180-6. 

Chunyi Yin, Hoa N. Dang, Hai-Bo Zhang, Farzad Gazor, Daniel Kim, Ole E. Sorensen, and George T.-J. Huang. Capacity of Human β-Defensin Expression in Gene-Transduced and Cytokine-Induced Cells.
Biochem. Biophys. Res. Comm. 2006 Jan 6;339(1):344-54. Epub 2005 Nov 15

Huang, G. T.-J., Sonoyama, W., Chen, J. and Park, S. H, In vitro characterization of human dental pulp cells –different isolation methods and culturing environments.
Cell Tissue Res Epub Jan. 2006

Arola, D., W. Zheng, J. A. Rouland, and N. Sundaram (2005) “Stress Ratio Contributes to Fatigue Crack Growth in Dentin,”
Journal of Biomedical Materials Research. 73A, (2), pp.201 - 212.

Arola, D. and R. Reprogel, (2005) “Effects of Aging on the Mechanical Behavior of Human Dentin,”
Biomaterials  26 (18):4051-4061. 

Arola, D. and R. Reprogel, (2006) “Tubule Orientation and the Fatigue Strength of Human Dentin,”
Biomaterials 27(9): 2131-2140.  

Arola, D., K. A. Stoffel, and D. T. Yang, (2006) “Fatigue of the Cement/Bone Interface: The Surface Texture of Bone and Loosening,”
Journal of Biomedical Materials Research: Applied Biomaterials 76B(2):287-297.

Textbooks and Textbook Chapters

Fouad AF, Levin L. Pulpal Reactions to Caries and Dental Procedures, Chapter 13 in: Pathways of the Pulp, Ninth Edition; Cohen S and Hargreaves K, Editors, Mosby, 2005.

Patents

Armellini, D.B., Shirtliff, M.E., Pazoki, A.E.: Reynolds M, Molly L. International Patent Application: “ Dental Implant Screw and Method of Use”  UMB Docket: DA-2005-060.

Armellini, D.B., Shirtliff, M.E., Pazoki, A.E.: Reynolds M, Molly L. Smart Delivery System on Joints

Armellini, D.B., Shirtliff, M.E., Pazoki, A.E.: Reynolds M, Molly L. Smart Delivery System on plates

Membrane distraction technique for bone formation Liene Molly,Debora B. Armellini, Mark E. Shirtliff, Mark A. Reynolds

Bioactive Glass and Methods of Treatment using Bioactive Glass for Gingivitis, Republic of Korea, 2005 Litkowski, LJ, Hack GD

Bioactive Glass and Methods of Treatment using Bioactive Glass for Gingivitis, PTO issued in 15 countries , 2005 Litkowski, LJ, Hack GD

Arola, D. Application for “Apatite Air Jet for Remineralizatin of Hard Tissues,” Invention Disclosure filed April, 2005

Abstracts

G D Hack. Foramen Ovale: Lateral Fossa: A Previously Undescribed Plastic Response of Bone to Pterygoid Muscle Forces. Program of the Seventy-Fourth Annual Meeting of the American Association of Physical Anthropologists. Milwaukee, Wisconsin. April 6 to April 9, 2005. American Journal of Physical Anthropology.

Fouad AF, Romberg E, Jones OJ. Web-based faculty calibration in predoctoral endodontics. J Dent Educ 2005: 69(1):148.

Kaufman BM, Spangberg LS, Barry J, Fouad AF. Endodontic Failure: Correlation to Microbiological and Clinical Factors. J Dent Res 2005, March Special issue. Abstract #1592

Fouad AF, Barry J., Pimblett T., Cox E Endodontic microbial analysis using specific versus universal PCR primers. J Dent Res 2005, March Special issue. Abstract #2606.

Kaufman BM, Spangberg LS, Fouad AF. Enterococcus spp. in endodontically-treated teeth with and without periradicular lesions. J Endod 2005: 31 (3): 217.

Fouad AF, Barry J., Pimblett T., Cox E Endodontic microbial analysis using specific versus universal PCR primers. J Dent Res 2005, March Special issue. Abstract #2606.

Kaufman BM, Spangberg LS, Fouad AF. Enterococcus spp. in endodontically-treated teeth with and without periradicular lesions. J Endod 2005: 31 (3): 217.

Chunyi Yin*, H.N. Dang, F. Gazor, George T.-J. Huang. Mouse salivary gland model for antimicrobial gene therapy--technical considerations. J. Dent. Res., 2006

K. Shagramanova*, S. W. Chen, P. Aurasteh, I. Tam, G.T.-J. Huang. In vitro formation of odontoblast-like cells on dentin. J. Dent. Res., 2006

Hayes P, Strassler HE.  Multimedia with an interactive computer program for dental anatomy and occlusion, ADEA, Orlando, FL, March, 2006

Strassler HE, Suh BI, Wang,  Y.  Compatibility of glass ionomer cements with desensitizing agents.  JDR (Special Issue, abstracts), March 2006 (poster at AADR, Orlando, FL)

Water sorption and compressibility of Liner Materials. D. Armellini*, J. Kato, J.A. Von Fraunhofer ,Dental School, University of Maryland, Baltimore, MD, USA,  J Dent Res 2006

Cox ME, Reprogel RK, Bajaj D, Skane TL, Fouad AF, and Arola DD. Tubule Orientation, Calcium Hydroxide and the Fatigue Strength of Dentin. J Dent Res 2006, March Special issue. Abstract #2058.

Murtaza G, Fouad AF, Molecular Analysis of Persistent Endodontic Microflora and Their Effect on Treatment Outcome. J Endod 2006: 32 (3): 240.

Skane TL, Bajaj D, Cox ME, Arola DD and Fouad AF. Fatigue resistance of human root dentin exposed to intracanal calcium hydroxide. J Endod 2006: 32 (3): 244.

Mirchandani R, Nandakumar R, Fouad AF. Primer sensitivity: Can it influence the results of Enterococcus faecalis prevalence studies? J Endod 2006: 32 (3): 258.

Cook J, Nandakumar R, Patel S, Rajaski J, Fouad, AF. Molecular and culture-based analyses of the persistence of polymicrobial inoculum in infected dentinal tubules after obturation. J Endod 2006: 32 (3): 254.

Soappman M, and Arola D. Fatigue Crack Growth through Resin Composite and the Adhesive Interface.  J Dent Res 2006, March Special issue. Abstract #1312.

Cox ME, Reprogel RK, Bajaj D, Skane TL, Fouad AF and Arola D. Tubule Orientation, Calcium Hydroxide, and the Fatigue Strength of Dentin.  J Dent Res 2006, March Special issue. Abstract #2058

Bajaj D, Sundaram N, Nazari A, and Arola D. Aging Contributes to the Fatigue Crack Growth Resistance of Dentin. J Dent Res 2006, March Special issue. Abstract #2071.